Home » Comments
Comments on scientific papers
Here you can search and comment any existing scientific paper: use the search functionality to find the paper you want to comment on. The comments will be forwarded to the corresponding article authors (when possible) and all comment subscribers - identified user can invite additional persons to join the discussion about a specific article.
Latest commented articles
MicroRNAs in Brain Metastases: Potential Role as Diagnostics and Therapeutics, International Journal of Molecular Sciences, 2014, 10.3390/ijms150610508
2 Comments → add new, Samer Alsidawi, Ehsan Malek, James Driscoll
Brain metastases remain a daunting adversary that negatively impact patient survival. Metastatic brain tumors affect up to 45% of all cancer patients with systemic cancer and account for ~20% of all cancer-related deaths. A complex network of non-coding RNA molecules, microRNAs (miRNAs), regulate tumor metastasis. The brain micro-environment modulates metastatic tumor growth; however, defining the precise genetic events that promote metastasis in the brain niche represents an important, unresolved problem. Understanding these events will reveal disease-based targets and offer effective strategies to treat brain metastases. Effective therapeutic strategies based upon the biology of brain metastases represent an urgent, unmet need with immediate potential for clinical impact. Studies have demonstrated the ability of miRNAs to distinguish normal from cancerous cells, primary from secondary brain tumors, and correctly categorize metastatic brain tumor tissue of origin based solely on miRNA profiles. Interestingly, manipulation of miRNAs has proven effective in cancer treatment. With the promise of reduced toxicity, increased efficacy and individually directed personalized anti-cancer therapy, using miRNA in the treatment of metastatic brain tumors may prove very useful and improve patient outcome. In this review, we focus on the potential of miRNAs as diagnostic and therapeutic targets for the treatment of metastatic brain lesions.
Proteolysis Inhibitor E-Aminocaproic Acid as Effective Drug for Prevention and Treatment of Influenza, Other Acute Respiratory Viral Infections and their Bacterial Complications, 1st International Electronic Conference on Medicinal Chemistry, 2015, 10.3390/ecmc-1-A050
7 Comments → add new, V. Lozitsky, A. Fedchuk, T. Grydina, L. Shytikova, L. Mudryk, S. Socheslo, M. Lebediuk, O. Voronkov, V. Trykhlib, A. Frolov, V. Zadorozhna, V. Buiko, S. Tkachuk
Using Celebrities in Abnormal Psychology as Teaching Tools to Decrease Stigma and Increase Help Seeking, Teaching of Psychology, 2016, 10.1177/0098628316662765
1 Comment → add new, Anne Ferrari
Research shows that a very small percentage of those who suffer from mental illness seek professional help and fear of stigma is a principal factor why individuals are reluctant to obtain assistance. This study evaluated whether using examples of celebrities’ experiences with mental illness as a form of “contact” with a mentally ill person would reduce public stigma toward mental illness as well as stigma toward obtaining psychological assistance. Data were collected using a pre–post design from 38 (experimental group) and 17 (control group) college undergraduate students enrolled in an abnormal psychology course. Compared to the control group, the use of celebrities as narratives to teach about mental illness resulted in reduced public stigma toward mental illness and reduced stigma toward seeking help.
Enhanced Detection of Human Plasma Proteins on Nanostructured Silver Surfaces, Nanomaterials and Nanotechnology, 2013, 10.5772/56940
1 Comment → add new, Zuzana Orsagova, Andrej Orinak, Renata Orinakova, Lenka Skantarova, Jozef Radonak, Andrej Oriňák Zuzana Orságová Králová
A New Concept in Pumping Unit Technology, SPE Hobbs Petroleum Technology Symposium, 1970, 10.2118/3193-ms
1 Comment → add new, E.W. Metters
The Problematic Forms of Nominalization in English: Gerund, Verbal Noun, and Deverbal Noun, English Linguistics Research, 2014, 10.5430/elr.v4n1p30
1 Comment → add new, Inam Ismael Taher
Deformation of Pure Aluminum Along the Groove Path of ECAP-Conform Process, Advanced Engineering Materials, 2015, 10.1002/adem.201500251
1 Comment → add new, Vahid Ayati, Mohammad Habibi Parsa, Hamed Mirzadeh
Combining of rotary extrusion and equal channel angular pressing (ECAP) leads to the ECAP-Conform process, which is one of the few successful continuous severe plastic deformation processes. Sample before reaching the ECAP die is influenced by three main deformations of rolling, bending, and forging, which can affect the microstructure and mechanical properties of the material. The effects of these steps on the microstructure and properties of AA1100 alloy are studied based on the simulation and experimental investigations. It is found that these steps significantly affect the material and they should be considered for evaluation of properties compared with the conventional ECAP.
Coordination and Subordination in the Kenyang Language, Journal of Foreign Languages, Cultures and Civilizations, 2015, 10.15640/jflcc.v3n1a2
1 Comment → add new, Mbu Martha Njui
Coordination and Subordination in the Kenyang Language Mbu Martha Njui Abstract Coordination and Subordination are common but important syntactic phenomena exhibited by natural languages. In investigating these phenomena, scholars have paid attention to its associated syntactic features such as the connecting devices, structural types, compression rules and constraining principles. Like many other languages, Kenyang employs two major strategies to conjoin phrases and clauses. These are the overt and the covert strategies. Talking about the overt strategy, the conjuncts of the coordinate structure are united by an overt morphological or phonological coordinating conjunction, while in the covert strategy the conjuncts are not united by any of such overt coordinating conjunction. Subordinate clauses in Kenyang on their part are marked by special subordinating morphemes which denote time, purpose, condition and concession. This paper describes the structure of both coordinating and subordinating phenomena in Kenyang (a Bantu Language spoken in the South West region of the republic of Cameroon). The structural approach is adopted in the data presentation to highlight on some cross- linguistic universals on coordination and subordination in order to properly characterize these linguistic features in Kenyang. Full Text: PDF DOI: 10.15640/jflcc.v3n1a2
Raney Nickel for the Desulphurization of FCC Gasoline, Journal of Canadian Petroleum Technology, 2006, 10.2118/06-11-06
1 Comment → add new, J.A. Hendsbee, R.W. Thring, D.G. Dick
Analysis of Efficiency of Classification and Prediction Algorithms (kNN) for Breast Cancer Dataset, Advances in Intelligent Systems and Computing, 2016, 10.1007/978-81-322-2752-6_18
1 Comment → add new, G. D. Rashmi, A. Lekha, Neelam Bawane