There have many categories of human body medicine existed in the world. Two of them are in China, namely Traditional Chinese Medicine and Western Medicine. Both of them have achieved good results on one hand and been facing problems,owing to the different methodologies - reductionism for Western Medicine and Ecology-ism for Traditional Chinese Medicine. It is explained in the paper that there is a need for integration of the two methodologies for the complex human body medicine study.This is really the challenge to human body medicine study.