A study of the regioisomerism in pyrazole alkylation using environmental friendly microwave irradiation

M. Blanco; R. Claramunt,; C. Escolástico; D. Sanz

doi:10.3390/ecsoc-10-01440

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A study of the regioisomerism in pyrazole alkylation using environmental friendly microwave irradiation

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¹ Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, Universidad Nacional de Educación a Distancia (UNED), Senda del Rey 9, E-28040 Madrid, Spain

Published: 30 November 2006 by MDPI in The 10th International Electronic Conference on Synthetic Organic Chemistry session Symposium on Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-10-01440

Abstract: Pyrazole alkylation by benzyl, diphenylmethyl and trityl halides (chlorides and bromides) has been achieved by means of microwave irradiation. The structures and percentages of the different derivatives obtained have been determined by analytical methods: NMR spectroscopy plus gas chromatography coupled to mass spectrometry.

Keywords: Microwaves, pyrazoles, aralkyl halides

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