Welcome from the Chair

Welcome to The 15th International Electronic Conference on Synthetic Organic Chemistry

Call for Papers

The research concerned with synthetic organic chemistry is progressing fast and simultaneously, activities within both industry and academy are becoming more globalized. Successful research requires interaction with several units around the world. We are facing an obvious need for new and fast types of communication within our scientific community. Sciforum.net electronic conferences provide a platform for fast exchange of the latest research findings, as well as a possibility for global meetings with no limitations related to traveling.

The 15th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-15) will run from 1 - 30 November 2011. ECSOC-15 Proceedings will be published later online and as a CD-ROM edition (ISBN: 3-906980-25-1). Posters presented at ECSOC-15 may be considered as preliminary communications of new research results or review papers and may be published in another form later in any standard journal. At the authors discretion, contributions will be removed from the web-site after the end of the conference and not included in the online and CD-ROM proceedings editions. Authors are invited to publish their papers subsequently in Molecules.

The 15th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-15) will cover timely research topics concerned with synthetic organi chemistry. The conference will be divided into 5 topical sessions. The first session wil be related to general organic synthesis (Section A). The second session will focus on bioorganic, medicinal and natural products (Section B). The third session will be a symposium on microwave assisted aynthesis (Section C). The fourth session will be related to polymer and supramolecular chemistry (Section D). Finally, the last session will focus on computational chemistry (Section E).

Conference Chairs

Julio A. Seijas

Universidad de Santiago de Compostela

Sessions

A. General Organic Synthesis
B. Bioorganic, Medicinal and Natural Products
C. Microwave Assisted Synthesis
D. Polymer and Supramolecular Chemistry
E. Computational Chemistry

Instructions for Authors

Procedure for Submission, Peer-Review, Revision and Acceptance of Conference Proceedings Papers

1. Scholars interested in participating with the conference can submit their abstract (about 200-300 words covering the areas of Communications for the proceedings issue) online on this website until 30 September 2011.

2. The conference committee will pre-evaluate, based on the submitted abstract, whether a contribution from the authors of the abstract will be welcome for this 15th edition of ECSOC. All authors will be notified by 10 October 2011 about the acceptance of their abstract.

3. If the abstract is accepted for this conference, the author is asked to submit his full communication paper, optionally along with a PowerPoint presentation of his/her paper, until the submission deadline of 20 October 2011.

4. The conference committee will then organize a round of peer-review of the submitted communication papers, and authors are eventually asked to revise their paper based on peer-reviewer's comments.

5. Finally, accepted communication papers will appear on the website immediately after their acceptance.

6. Presented communications papers can be discussed, commented and rated during the time of the conference, 1-30 November 2011.

Proceedings Paper

Communications for the proceedings issue must have the following organization:

Firstpage:

Title

Full author names

Affiliations and authors' e-mail addresses

Abstract

Keywords

Introduction

Methods / Experim

Results and Discussion

Conclusions

(Acknowledgements)

References

Communications should be prepared in MS Word or any other word processor and should be converted to the PDF format before submission. The publication format will be PDF. The Communication paper should count at least 3 pages (incl. figures, tables and references). There is no page limit on the length, although authors are asked to keep their papers as concise as possible.

Presentation Slides
Authors are encouraged to preare a couple of slides in PowerPoint or similar software, to be displayed online along with the Communication. Slides, if available, will be displayed directly in the website using Sciforum.net's proprietary slides viewer. Slides can be prepared in exactly the same way as for any traditional conference where research results can be presented. Slides should be converted to the PDF format before submission so that our process can easily and automatically convert them for online displaying.

Submission
Submissions should be done by the authors online by registering with www.sciforum.net, and using the "New Submission" function once logged into system.

Copyright
MDPI AG, the publisher of the Sciforum.net platform, is an open access publisher. We believe that authors should retain the copyright to their scholarly works. Hence, by submitting a Communication paper to this conference, you retain the copyright of your paper, but you grant MDPI AG the non-exclusive right to publish this paper online on the Sciforum.net platform. This means you can easily submit your paper to any scientific journal at a later stage and transfer the copyright to its publisher (if required by that publisher).

List of accepted submissions (97)

Id	Title	Authors	Poster PDF
sciforum-001956	Synthesis of furo[3,2-b]pyrrole-5-carboxhydrazides and Their Cu, Ni and Co Complexes Mária Maliarová , Tatiana Ďurčeková , Filip Kraic , Ján Titiš , Renata Gašparová Submitted: 19 Sep 2011 Abstract: Show Abstract	Mária Maliarová , Tatiana Ďurčeková , Filip Kraic , Ján Titiš , Renata Gašparová	N/A	Show Abstract
N\'-[(4-oxochromen-3-yl)methylidene]-4-R-furo[3,2-b]pyrrole-5-carboxhydrazides 3 were prepared by treatment of substituted carboxhydrazides 1 with 4-oxo-4H-chromen-3-carboxaldehyde 2 in ethanol in the presence of p-TsOH. Compounds 3 were subsequently used as ligands in complexation reactions with solutions of metal (M²⁺) chlorides or nitrates: [Ni(NO₃)₂.6H₂O, Co(NO₃)₂.6H₂O, CoCl₂.6H₂O, CuCl₂.2H₂O] to give complexes 4.
sciforum-001957	Alternative synthetic approaches to biologically active indeno[1,2-c]isoquinoline-5,11-diones Pierre Grandclaudon , Eric Deniau , Axel Couture , Stéphane Lebrun , Mélanie Dubois Submitted: 26 Sep 2011 Abstract: Show Abstract	Pierre Grandclaudon , Eric Deniau , Axel Couture , Stéphane Lebrun , Mélanie Dubois	N/A	Show Abstract
Indenoisoquinolinediones, as exemplified by lead compounds indotecan and indimitecan, are a class of non-camptothecin topoisomerase I poisons that display marked cytotoxic properties and for some of them antitumor activities in xenograft models. We have developed two alternative and dramatically different synthetic approaches to a variety of highly fused and diversely substituted models that differ from the elaboration of key precursors, i.e. arylated 2,3-dihydroisoquinolones. The first one is based upon a Suzuki-Miyaura cross-coupling reaction involving enol phosphates combined with a ring-closing metathesis (RCM) reaction to ensure the creation of the six-membered lactam unit. The second approach hinges upon the photoinduced electrocyclization of the 6π electron aromatic enamides. The presence of phenolic methoxy groups precluded an additional mandatory and problematic oxidation step to generate the unsaturated lactam ring. Intramolecular carbocationic annulation reaction and ultimate oxidation of the latent hydroxyl functionality completed the synthesis of the targeted title compounds.
sciforum-001961	Convenient synthesis of functionalized α-methylenebutano-4-lactams or lactones Pierre Grandclaudon , Axel Couture , Stéphane Lebrun , Gwenaëlle Liberge Submitted: 19 Sep 2011 Abstract: Show Abstract	Pierre Grandclaudon , Axel Couture , Stéphane Lebrun , Gwenaëlle Liberge	N/A	Show Abstract
α-Alkylidene-γ-lactams and lactones are the active constituents of many natural and synthetic compounds exhibiting pronounced biological properties. They are able to act as Michael acceptors in the reaction with thiol groups of bionucleophiles or can readily form [2 + 2] cycloadducts with DNA bases. We have developed concise synthetic approaches towards exemplary representatives of α-methylene models that hinges upon the preliminary assembly of the lactam and lactone template. Subsequent installation of the methylidene by a metallation/alkylation/elimination sequence completed the elaboration of the racemic title compounds. The presence of a quaternary carbon center bearing the carboxylate function precluded the undesirable isomerization leading to the corresponding endocyclic unsaturated analogues.
sciforum-001965	Silylation of cellobiose as a model reaction for the synthesis of silylated cellulose. A DFT and PM3 approach. Karin Stana-Kleinschek , Volker Ribitsch , Heike Ehmann , Stefan Spirk Submitted: 19 Sep 2011 Abstract: Show Abstract	Karin Stana-Kleinschek , Volker Ribitsch , Heike Ehmann , Stefan Spirk	N/A	Show Abstract
The object of the present study is the isodesmic reaction of cellobiose (the repeating unit in cellulose) with different kinds of silanes, R-SiH₃, to form silylated cellobiose (Cello-SiH₃) and the corresponding alcohols (R-OH). The size and the chemical reactivity of the substituent R is varied as well as the position where O-silylation at the cellobiose takes place. In contrast to experimental observations where the O6 position is favored for silylation, for the computed reactions, energy differences are smaller than 3 kcal/mol for the different positions at the B3LYP/6-311G* as well as at the B3LYP/6-311+G* level of theory. Depending on the silane, reaction energies in a range from -17 kcal/mol (R=NHSiH₃) and +18 kcal/mol (R=F) have been calculated. In addition, semi-empirical calculations on the PM3 level of theory have been performed. These results are set into contrast with the results derived from DFT calculations to assess whether semi-empirical methods may be useful for the description of larger systems containing silylated cellobiose units. Acknowledgements: The research leading to these results has received funding from the European Community\'s Seventh Framework Programme [FP7/2007–2013] under grant agreement no. 214015 (S.S. and H.M.A.E.) and no. 214653.
sciforum-001979	Synthesis and properties of cyclodextrin-malic acid copolymers Magdalena Marciniak , Marcin Lukasiewicz Submitted: 21 Sep 2011 Abstract: Show Abstract	Magdalena Marciniak , Marcin Lukasiewicz	N/A	Show Abstract
Cyclodextrins polymers are known as an interesting low molecular carriers in pharmacy, food technology, medicine etc. There are different routes to design such kind of macromolecules however most of them base on synthetic compound. In the presented work a series of cyclodextrin polyesters with malic acid were obtained using dry method. Sodium hydrogen phosphate was used as a catalyst. As a result two different fractions were obtained i.e. water soluble and insoluble ones. Both of them were characterized by means of carboxylic acid (HPLC) and carbohydrates profile (anthron method) . Several malic acid derivatives were detected especially fumaric and malonic acids. In obtained sample the complexation ability was checked using standard methyl orange method. The insoluble fraction was hydrolyzed using sodium carbonate solution and the carboxylic acids and cyclodextrin presence were investigated as well. According to obtained results we can state the novel cyclodextrin macromolecules were design using simple and easy protocol. The obtained product is fully biodegradable and completely nontoxic what guides to many possible application in both food and non-food application.