Human rhino viruses (HRVs) serve as an imperative precursor for frequent cases of the common cold among children worldwide. An in-silico molecular docking attempt was made of some chief phytochemical entities (Arisaema plant species) as inhibitors of HRVs with selective therapeutic target action and minimal side effects. Around 60 phytoconstituents of different Arisaema species were docked against HRV receptor (PDB: 2XYA). Binding conformers of test ligands were compared with internal ligand. Finally, Syringaresinol 4'-O-β-D-glucopyranoside (glide score: -10.86), Rutin (glide score: -9.04) & Apigenin-6,8-di-C-β-D-glucopyranoside (glide score: -7.88) have resulted in most promising hits which can be further act as an effective template to experimentally validate or further designed their choosy and budding analogue agents against HRVSs.