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Synthesis of new spiro pyrido[3',2':4,5]thieno[3,2-d]pyrimidines
1 , 1 , * 1, 2, 3 , 1, 4
1  Kuban State University, 149 Stavropolskaya Str., Krasnodar 350040, Russian Federation
2  ChemEx Lab, Vladimir Dal’ Lugansk National University, Lugansk, 91034 Russia.
3  North-Caucasus Federal University, 1 Pushkina St., 355009 Stavropol, Russian Federation
4  All-Russian Research Institute of Biological Plant Protection, Laboratory of plant growth regulators, 350039 Krasnodar, Russian Federation

Abstract:

A library of new  spiro pyrido[3',2':4,5]thieno[3,2-d]pyrimidines was synthesized by reaction of 3-aminothieno[2,3-b]pyridine-2-carboxamides with ninhydrin hydrate. The optimal reaction conditions and mechanism are discussed.

Keywords: spiro compoinds, indane-1,2,3-trione, thieno[2,3-b]pyridines, pyrido[3',2':4,5]thieno[3,2-d]pyrimidines
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