Host-Guest Chemistry of Tolbutamide

F. Herranz; M. Santa María; Rosa Claramunt

doi:10.3390/ecsoc-9-01517

Previous Article in event

Butorphanol Metabolites: Synthesis of Cis- and Trans-3,14-dihydroxy-N-(3'-hydroxycyclobutylmethyl) Morphinan

Next Article in event

Synthesis and Structure of Transition Metal Bisalkinylselenolato Complexes

Host-Guest Chemistry of Tolbutamide

F. Herranz

^*,

M. Dolores Santa María

Rosa M. Claramunt

¹ Departamento de Química Orgánica y Bio-Orgánica, Universidad Nacional de Educación a Distancia (UNED), Facultad de Ciencias, Senda del Rey 9, E-28040 Madrid, Spain

Published: 01 November 2005 by MDPI in The 9th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products

https://doi.org/10.3390/ecsoc-9-01517

Abstract: The molecular recognition features of tolbutamide with four synthetic hosts have been studied by means of NMR titrations, NOESY experiment and Monte Carlo (MC) conformational search. The interaction strength and the most probable structure reveal new insights on the recognition phenomena of this urea derivative in comparison with close related compounds.

View paper

51 Reads
0 Recommendations

F. Herranz

M. Santa María

Rosa Claramunt