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CELL REFRACTIVE INDEX IMAGING FOR REAL-TIME VIRUS INFECTION
1 , 2 , * 2 , 2 , 2 , 3 , 3 , 1 , 1 , 2
1  Université Paris-Est
2  Nanyang Technological University
3  DSO National Laboratories

Abstract:

This paper presents a new optofluidic detection system to measure the absolute refractive index map of host cells.  This new system: cell refractive index tomography, can measure the absolute refractive index map of host cells. During virus infection, cell morphology and the intracellular contents of the host cells are changed. Such changes can be monitored by detecting the refractive index variation. By monitoring of the cell’s refractive index, the detection of virus infection in real-time and label-free is determined.

Keywords: Optofluidic, refractive index map, label-free
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