On behalf of the journal Biomolecules (https://www.mdpi.com/journal/biomolecules), we introduce the discussion group “Intrinsically Disordered Proteins and the Janus Challenge”.
To gain insight into the role of proteins in the origin of life on Earth, two leading experts in the field of intrinsically disordered proteins (IDPs) and the current Editors-in-Chief of the journal Biomolecules, Dr. Prakash Kulkarni and Dr. Vladimir N. Uversky, presented the Janus Challenge. This challenge consists in identifying an IDP, naturally occurring or synthetic, that has catalytic activity. Meeting this challenge may not only shed new light and even provide an alternative to the RNA world hypothesis, but may also serve as an impetus for technological advances with important biomedical applications.
A more comprehensive description of the Janus Challenge was published as an Editorial in the journal Biomolecules: https://www.mdpi.com/2218-273X/8/4/179
In order to support the Janus Challenge and improve the communication within the IDP community, we have opened this discussion group. Herewith, we aim to set in motion a debate in which every scientist can share their interesting ideas and points of views regarding the science behind the Janus Challenge.
The use of plant in vitro (bio)technologies offers an attractive alternative for the production of plant-based active ingredients. Plant cells are small factories able to synthesize an exceptional variety of commercially important phytochemicals used as flavors, dyes, pharmaceuticals, nutraceuticals, cosmeceuticals, etc. Conventional plant propagation techniques are subjected to variety of pests, environmental challenges and poor management practices that adversely affect the quality and yield of these valuable phytochemicals. Plant in vitro culture platform offers considerable advantages and advancements over conventional phytochemical production techniques. However, during culture development, the yield of metabolites is generally low due to poor understanding of various factors that affect the biosynthetic pathway. Therefore, various strategies have been developed and reported to enhance biosynthesis of these phytochemicals in plant cell cultures. The recent emergence of omics technologies, molecular biology, metabolic engineering and synthetic biology has revolutionized diverse fields in life sciences. These modern aspects of life sciences have considerably influencing plant in vitro technology and phytochemical production. An application of these technologies is expanding horizons for an understanding of metabolic pathways involved in the biosynthesis of valuable biologically active ingredients and their cost-efficient production.
Essential Oils: From Phytochemistry to Ecophysiological Significances and Their Applications
In modern sustainable industries, “green products”, based on natural compounds, are of the highest importance. From this standpoint, essential oils are considered the most widely used natural products in many areas. Most of them have been used as fragrances, flavoring agents or as medicines since ancient times. At present, a renaissance of the research on essential oils in the traditional but also new industries is observed. Essential oils are extensively studied to treat various human ailments, for their potential cosmetic applications, but also for crop protection, as so-called botanical pesticides. This Special Issue is in connection with the Biological Activities of Essential Oils International Conference by Le Studium with the aim to give an overview of the modern biological applications and activities of essential oils. In addition, their phytochemistry and ecophysiological significances are also considered. For that purpose, original research articles, reviews, industrial cases, and short communications are also welcomed and encouraged.
Special Issue from Plants (MDPI):
Deadline for manuscript submissions: 30 November 2019
International Conference from Le Studium Loire Valley Institute for Advanced Studies
Please find additional information on this Conference at: http://www.lestudium-ias.com/event/biological-activities-essential-oils