Studies indicate that an emerging threat faces our freshwater and marine ecosystems plastic pollution. Since plastics are cheap, versatile and strong and deliver significant societal benefits, it comes as no surprise that plastic production has increased exponentially since the 1960’s. If current practices continue as usual, by 2025 there could be 1 ton of plastic for every 3 tons of fish in the ocean. With the ability to persist for up to 4 centuries, plastic products are harming freshwater and marine ecosystems. We have to find the solutions to protect our planet.
Overview: Plants perceive the world without eyes, ears or brains. For this reason, their perception mechanisms have been too often overlooked. Being alive, they exhibit behaviour, mostly unknown and secrete to humans. Plants fight for territory, seek out food, evade predators and trap prey. They have a chemical language for communicating with other plants of the same or other species, and with fungi and animals too. Plants move slowly but with purpose, which means they are aware of what is going on around them. They are attracted by certain chemicals and sounds, while avoid others. Also, analogues for mechanoreceptors, photoreceptors and neurotransmitters have been found in plants. Understanding how can teach us a lot about them, and potentially a lot about us as well.
Proposal submitted by: Dr. Adriano Sofo, Department of European and Mediterranean Cultures: Architecture, Environment and Cultural Heritage (DiCEM), University of Basilicata, Via Lanera, 20, 75100 Matera, Italy
Actually many diseases in neurodegeneration (Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, parkinson, and others) and in neurodevelopment (bipolar disorders, schizophrenia, fetal alcohol syndrom, and others) are strongly related to inflammation. In some diseases, as Alzheimer's disease (AD), a clear relationship between a special virus and AD has been detected. A virus is a DNA or RNA that proced from a cell. This cell can death by apoptosis or necrosis because a toxic action by the enviorament or by human actions. In this group we can discuss the genetic, molecular biology, the different proteins in the viruses and the diseases that they can produced in the nervous system.
On behalf of the journal Biomolecules (https://www.mdpi.com/journal/biomolecules), we introduce the discussion group “Intrinsically Disordered Proteins and the Janus Challenge”.
To gain insight into the role of proteins in the origin of life on Earth, two leading experts in the field of intrinsically disordered proteins (IDPs) and the current Editors-in-Chief of the journal Biomolecules, Dr. Prakash Kulkarni and Dr. Vladimir N. Uversky, presented the Janus Challenge. This challenge consists in identifying an IDP, naturally occurring or synthetic, that has catalytic activity. Meeting this challenge may not only shed new light and even provide an alternative to the RNA world hypothesis, but may also serve as an impetus for technological advances with important biomedical applications.
A more comprehensive description of the Janus Challenge was published as an Editorial in the journal Biomolecules: https://www.mdpi.com/2218-273X/8/4/179
In order to support the Janus Challenge and improve the communication within the IDP community, we have opened this discussion group. Herewith, we aim to set in motion a debate in which every scientist can share their interesting ideas and points of views regarding the science behind the Janus Challenge.