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Notes Towards a Network Approach to Gene Orientation
Viviana Quevedo 1 , Bernabé Ortega-Tenezaca 2 , Julio César Vargas-Burgos 2 , Alejandro Pazos-Sierra 1 , Humbert González-Díaz 3

1  RNASA-IMEDIR, Computer Science Faculty, University of A Coruña, 15071, A Coruña, Spain
2  Universidad Estatal Amazónica
3  Dept. of Organic Chemistry II, University of the Basque Country UPV/EHU, 48940, Leioa, Biscay, Spain

Published: 19 December 2017 by MDPI AG in Proceedings of MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition in MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition
MDPI AG, 10.3390/mol2net-03-05092
Abstract:

The distribution of the orientation genes in chromosomes is not random and may have function implications. In this work, we used complex networks to study the orientation of genes. We used as a case of study the 14 chromosomes of Plasmodium falciparum. We constructed the respective 14 networks with an average of 383 nodes (genes) and 1314 links (pairs of gene with inverse orientation). Node centralities of these nodes were used to study the structure of the network.


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