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Papers from Scilit (113 575 490)
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Studies of the Conservation Process and Taxonomy of Cycas baiseensis and Cycas debaoensis
Yu-Yuan Huang
Published: 09 November 2018 by New York Botanical Garden in Cycad Biology and Conservation: The 9th International Conference on Cycad Biology
New York Botanical Garden, 10.21135/893275389.032
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Thermogenesis Patterns in Selected Cycas Species
Irene Terry, Claudia Calonje, Michael A. Calonje, Thomas E. Marler
Published: 09 November 2018 by New York Botanical Garden in Cycad Biology and Conservation: The 9th International Conference on Cycad Biology
New York Botanical Garden, 10.21135/893275389.027
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Spent Coffee Grounds, Insect Control, and Plant Health in Cycads
Tracy Magellan, M. Patrick Griffith, Chad E. Husby, Stella Cuestas
Published: 09 November 2018 by New York Botanical Garden in Cycad Biology and Conservation: The 9th International Conference on Cycad Biology
New York Botanical Garden, 10.21135/893275389.022
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Practical implementation of the sine condition test
David Sommitz, Matthew Dubin
Published: 09 November 2018 by The Optical Society in Applied Optics
The Optical Society, Volume 57; 10.1364/ao.57.009699
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Platelet Function During Extracorporeal Membrane Oxygenation in Adult Patients: A Systematic Review
Camilla Mains Balle, Anni Nørgaard Jeppesen, Steffen Christensen, Anne-Mette Hvas
Published: 09 November 2018 by Frontiers Media SA in Frontiers in Cardiovascular Medicine
Frontiers Media SA, Volume 5; 10.3389/fcvm.2018.00157
Background: Hemorrhagic and thromboembolic complications are common during treatment with extracorporeal membrane oxygenation (ECMO), resulting in considerable morbidity and mortality. This emphasizes the clinical relevance of understanding hemostatic changes occurring during ECMO treatment. As platelets are key players in hemostasis, detailed knowledge on how ECMO treatment affects platelet function is of great importance. We therefore aimed to systematically summarize and discuss existing knowledge on platelet function during ECMO treatment in adult patients. Methods: Systematic review complying with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Objectives and methods were specified in a PROSPERO protocol (ID no CRD42018084059). The MEDLINE/PubMed, EMBASE, and Web of Science databases were systematically searched on September 10, 2018. A standardized quality assessment tool was used to assess the risk of bias in included studies. Primary outcome was platelet function during ECMO treatment, measured as platelet adhesion, activation or aggregation. Secondary outcomes were thrombosis, bleeding, and mortality during ECMO treatment. Results: A total of 591 studies were identified, of which seven were eligible for inclusion in the qualitative synthesis. Of these, one study investigated expression of platelet adhesion receptors and found them to be reduced during ECMO treatment; two studies reported a decrease in platelet activation markers during ECMO treatment; and five studies demonstrated reduced platelet aggregation during ECMO treatment. Three studies reported on thrombosis, mortality and/or bleeding during ECMO treatment; no thromboembolic events were reported; all three studies reported frequent bleeding episodes defined on basis of transfusion requirements. An in-hospital mortality of 35–40% and a 30-day mortality of roughly 30% were reported in three different studies. Conclusions: The present systematic review reveals a substantial knowledge gap regarding platelet function during ECMO treatment in adult patients and underscores the demand for more and well-designed studies on this topic. There is suggested evidence of reduced platelet adhesion, decreased platelet activation, and reduced platelet aggregation in adult patients during ECMO treatment. Importantly, platelet aggregation results need to be interpreted in the light of low platelet counts. The associations of platelet function and bleeding and/or thromboembolic complications during ECMO treatment remain to be fully elucidated.
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