Distribution of Articles published per year
Total number of journals
Article 2 Reads 4 Citations Development of novel adenosine receptor ligands based on the 3-amidocoumarin scaffold Published: 01 August 2015
Bioorganic Chemistry, doi: 10.1016/j.bioorg.2015.05.008
Article 0 Reads 1 Citation Potent and selective MAO-B inhibitory activity: Amino- versus nitro-3-arylcoumarin derivatives Published: 01 February 2015
Bioorganic & Medicinal Chemistry Letters, doi: 10.1016/j.bmcl.2014.12.001
Article 2 Reads 0 Citations N -(2-Oxo-2 H -chromen-3-yl)cyclohexanecarboxamide Published: 24 November 2012
Acta Crystallographica Section E Structure Reports Online, doi: 10.1107/S1600536812047903
In the title compound, C16H17NO3, the coumarin moiety is essentially planar [maximum deviation from the mean plane formed by the C and O atoms of the coumarin = 0.0183 (12) Å] and that the cyclohexane ring adopts the usual chair conformation. The dihedral angle between the mean plane of the coumarin residue and the plane of the amide residue (defined as the N, C and O atoms) is 18.9 (2)°. There are two intramolecular hydrogen bonds involving the amide group. In one, the N atom acts as donor to the ketonic O atom and in the other, the amide O atom acts as acceptor of a C-H group of the coumarin. In the crystal, molecules are linked into inversion dimers by pairs of N-HO contacts and these dimers are linked into pairs by weak C-HO hydrogen bonds. The combination of these interactions creates a chain of rings which runs parallel to [2-10]. C-H and - [centroid-centroid distance = 3.8654 (10) Å] interactions are also observed.
Article 2 Reads 1 Citation 3-Phenylcoumarin Published: 04 August 2012
Acta Crystallographica Section E Structure Reports Online, doi: 10.1107/S1600536812034277
In the title compound, C15H10O2, a 3-phenyl derivative of the coumarin (also known as 2H-chromen-2-one or 2H-1-benzopyran-2-one) scaffold, the Cp-Cp-Cc-Cc torsion angle between the coumarin (c) ring system and the phenyl (p) ring is -47.6 (2)°.