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Martha Harnly   Dr.  Research or Laboratory Scientist 
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Martha Harnly published an article in April 2011.
Top co-authors See all
Brenda Eskenazi

156 shared publications

Center for Children's Environmental Health, School of Public Health, University of California, Berkeley, 1995 University Avenue Suite 265, Berkeley, CA 94720, USA.

Dana Boyd Barr

105 shared publications

Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta GA 30322, United States

Thomas E. McKone

79 shared publications

School of Public Health, University of California, Berkeley, California, USA

Nina Holland

64 shared publications

Children's Environmental Health Laboratory, Global Berkeley Campus, University of California, Berkeley, 1301 S. 46th Street, Bldg 112, Richmond, CA 94804, USA.

Asa Bradman

58 shared publications

Center for Environmental Research and Children’s Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, California 94720, United States

Publication Record
Distribution of Articles published per year 
(2003 - 2011)
Total number of journals
published in
Article 1 Read 26 Citations Determinants of Organophosphorus Pesticide Urinary Metabolite Levels in Young Children Living in an Agricultural Communi... Asa Bradman, Rosemary Castorina, Dana Boyd Barr, Jonathan Ch... Published: 08 April 2011
International Journal of Environmental Research and Public Health, doi: 10.3390/ijerph8041061
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Organophosphorus (OP) pesticides are used in agriculture and several are registered for home use. As young children age they may experience different pesticide exposures due to varying diet, behavior, and other factors. We measured six OP dialkylphosphate (DAP) metabolites (three dimethyl alkylphosphates (DMAP) and three diethyl alkylphosphates (DEAP)) in urine samples collected from ∼400 children living in an agricultural community when they were 6, 12, and 24 months old. We examined bivariate associations between DAP metabolite levels and determinants such as age, diet, season, and parent occupation. To evaluate independent impacts, we then used generalized linear mixed multivariable models including interaction terms with age. The final models indicated that DMAP metabolite levels increased with age. DMAP levels were also positively associated with daily servings of produce at 6- and 24-months. Among the 6-month olds, DMAP metabolite levels were higher when samples were collected during the summer/spring versus the winter/fall months. Among the 12-month olds, DMAP and DEAP metabolites were higher when children lived ≤60 meters from an agricultural field. Among the 24-month-olds, DEAP metabolite levels were higher during the summer/spring months. Our findings suggest that there are multiple determinants of OP pesticide exposures, notably dietary intake and temporal and spatial proximity to agricultural use. The impact of these determinants varied by age and class of DAP metabolite.
Article 0 Reads 47 Citations Pesticides in house dust from urban and farmworker households in California: an observational measurement study. Lesliam Quirós-Alcalá, Asa Bradman, Marcia Nishioka, Martha ... Published: 16 March 2011
Environmental Health, doi: 10.1186/1476-069X-10-19
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Studies report that residential use of pesticides in low-income homes is common because of poor housing conditions and pest infestations; however, exposure data on contemporary-use pesticides in low-income households is limited. We conducted a study in low-income homes from urban and agricultural communities to: characterize and compare house dust levels of agricultural and residential-use pesticides; evaluate the correlation of pesticide concentrations in samples collected several days apart; examine whether concentrations of pesticides phased-out for residential uses, but still used in agriculture (i.e., chlorpyrifos and diazinon) have declined in homes in the agricultural community; and estimate resident children's pesticide exposures via inadvertent dust ingestion. In 2006, we collected up to two dust samples 5-8 days apart from each of 13 urban homes in Oakland, California and 15 farmworker homes in Salinas, California, an agricultural community (54 samples total). We measured 22 insecticides including organophosphates (chlorpyrifos, diazinon, diazinon-oxon, malathion, methidathion, methyl parathion, phorate, and tetrachlorvinphos) and pyrethroids (allethrin-two isomers, bifenthrin, cypermethrin-four isomers, deltamethrin, esfenvalerate, imiprothrin, permethrin-two isomers, prallethrin, and sumithrin), one phthalate herbicide (chlorthal-dimethyl), one dicarboximide fungicide (iprodione), and one pesticide synergist (piperonyl butoxide). More than half of the households reported applying pesticides indoors. Analytes frequently detected in both locations included chlorpyrifos, diazinon, permethrin, allethrin, cypermethrin, and piperonyl butoxide; no differences in concentrations or loadings were observed between locations for these analytes. Chlorthal-dimethyl was detected solely in farmworker homes, suggesting contamination due to regional agricultural use. Concentrations in samples collected 5-8 days apart in the same home were strongly correlated for the majority of the frequently detected analytes (Spearman ρ = 0.70-1.00, p < 0.01). Additionally, diazinon and chlorpyrifos concentrations in Salinas farmworker homes were 40-80% lower than concentrations reported in samples from Salinas farmworker homes studied between 2000-2002, suggesting a temporal reduction after their residential phase-out. Finally, estimated non-dietary pesticide intake for resident children did not exceed current U.S. Environmental Protection Agency's (U.S. EPA) recommended chronic reference doses (RfDs). Low-income children are potentially exposed to a mixture of pesticides as a result of poorer housing quality. Historical or current pesticide use indoors is likely to contribute to ongoing exposures. Agricultural pesticide use may also contribute to additional exposures to some pesticides in rural areas. Although children's non-dietary intake did not exceed U.S. EPA RfDs for select pesticides, this does not ensure that children are free of any health risks as...
Article 1 Read 25 Citations Pesticides in Dust from Homes in an Agricultural Area Martha E. Harnly, Asa Bradman, Marcia Nishioka, Thomas E. Mc... Published: 01 December 2009
Environmental Science & Technology, doi: 10.1021/es9020958
DOI See at publisher website PubMed View at PubMed
Article 0 Reads 1 Citation Merging models and biomonitoring data to characterize sources and pathways of human exposure to organophosphorus pestici... Thomas E Mckone, Rosemary Castorina, Martha E Harnly, Yu Kuw... Published: 01 May 2007
Environmental Science & Technology,
PubMed View at PubMed
Article 0 Reads 5 Citations Organophosphate urinary metabolite levels during pregnancy and after delivery in women living in an agricultural communi... Asa Bradman, Brenda Eskenazi, Dana B Barr, Roberto Bravo, Ro... Published: 01 December 2005
Environmental Health Perspectives,
PubMed View at PubMed
Article 3 Reads 25 Citations Cumulative organophosphate pesticide exposure and risk assessment among pregnant women living in an agricultural communi... Rosemary Castorina, Asa Bradman, Thomas E. McKone, Dana B. B... Published: 01 October 2003
Environmental Health Perspectives, doi: 10.1289/ehp.5887
DOI See at publisher website