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Prashanth Asuri   Dr.  Other 
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Prashanth Asuri published an article in December 2018.
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0 Enzymes
0 Ethanol
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Top co-authors See all
Hohyun Lee

16 shared publications

Guest Editor Mechanical Engineering Department, Santa Clara University, Santa Clara, CA 95053

Lim Mayasari

2 shared publications

Div. of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore;;; Correspondence concerning this article should be addressed to P. Asuri at

James Thomin

1 shared publications

Department of General Sciences, Northwest Florida State College, Niceville, FL 32578, USA

Josergio Zaragoza

1 shared publications

Department of Bioengineering, Santa Clara University, Santa Clara, CA 95053, USA;(J.Z.);(S.F.);(M.K.)

Marcus Kraus

1 shared publications

Department of Bioengineering, Santa Clara University, Santa Clara, CA 95053, USA;(J.Z.);(S.F.);(M.K.)

Publication Record
Distribution of Articles published per year 
(2013 - 2018)
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Article 0 Reads 0 Citations Solution effects on the self-association of a water-soluble peptoid Amelia A. Fuller, Jonathan Huber, Christian J. Jimenez, Kall... Published: 22 December 2018
Biopolymers, doi: 10.1002/bip.23248
DOI See at publisher website
Article 1 Read 0 Citations Exploring the Role of Nanoparticles in Enhancing Mechanical Properties of Hydrogel Nanocomposites Josergio Zaragoza, Scott Fukuoka, Marcus Kraus, James Thomin... Published: 29 October 2018
Nanomaterials, doi: 10.3390/nano8110882
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Over the past few decades, research studies have established that the mechanical properties of hydrogels can be largely impacted by the addition of nanoparticles. However, the exact mechanisms behind such enhancements are not yet fully understood. To further explore the role of nanoparticles on the enhanced mechanical properties of hydrogel nanocomposites, we used chemically crosslinked polyacrylamide hydrogels incorporating silica nanoparticles as the model system. Rheological measurements indicate that nanoparticle-mediated increases in hydrogel elastic modulus can exceed the maximum modulus that can be obtained through purely chemical crosslinking. Moreover, the data reveal that nanoparticle, monomer, and chemical crosslinker concentrations can all play an important role on the nanoparticle mediated-enhancements in mechanical properties. These results also demonstrate a strong role for pseudo crosslinking facilitated by polymer–particle interactions on the observed enhancements in elastic moduli. Taken together, our work delves into the role of nanoparticles on enhancing hydrogel properties, which is vital to the development of hydrogel nanocomposites with a wide range of specific mechanical properties.
CONFERENCE-ARTICLE 388 Reads 0 Citations Exploring the effects of nanoparticle incorporation on the mechanical properties of hydrogels. Josergio Zaragoza, Prashanth Asuri Published: 16 April 2018
Proceedings, doi: 10.3390/IOCN_2018-1-05191
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Recent studies have expanded our understanding of the effects of nanoparticles on hydrogel mechanical properties. However, further studies are needed to validate the generality of the findings, as well as to determine the exact mechanisms behind the enhancements afforded by the incorporation of nanoparticles. In this study, we performed rotational rheological characterizations of chemically crosslinked poly(acrylamide) hydrogels incorporating silica nanoparticles to better understand the role of nanoparticles on the enhanced properties of hydrogel nanocomposites. Our results indicate that the increases in elastic moduli due to the addition of nanoparticles depend strongly on particle size and concentration, as well as the overall concentration of the hydrogel. Moreover, we find that incorporating nanoparticles can lead to enhancements in hydrogel elastic moduli greater than the maxima obtainable through purely chemical crosslinking. Finally, our data indicates a strong role for pseudo-crosslinking mediated by non-covalent interactions between the nanoparticles and hydrogel polymers on the observed reinforcements. Collectively, our results shed further insight into the role of nanoparticles on enhancements of mechanical properties of polymers and may thereby facilitate engineering specific mechanical properties in a wide range of hydrogel nanocomposite systems.

Article 0 Reads 4 Citations Effect of crosslinker length on the elastic and compression modulus of poly(acrylamide) nanocomposite hydrogels J Zaragoza, A Chang, P Asuri Published: 01 January 2017
Journal of Physics: Conference Series, doi: 10.1088/1742-6596/790/1/012037
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Article 2 Reads 2 Citations Trehalose effectiveness as a cryoprotectant in 2D and 3D cell cultures of human embryonic kidney cells Jared Hara, Jordan Tottori, Megan Anders, Smritee Dadhwal, P... Published: 03 April 2016
Artificial Cells, Nanomedicine, and Biotechnology, doi: 10.3109/21691401.2016.1167698
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Article 3 Reads 7 Citations Three-dimensional matrix stiffness and adhesive ligands affect cancer cell response to toxins Silviya Petrova Zustiak, Smritee Dadhwal, Carlos Medina, Son... Published: 03 September 2015
Biotechnology and Bioengineering, doi: 10.1002/bit.25709
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