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Muthukumaran Packirisamy   Professor  Senior Scientist or Principal Investigator 
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Muthukumaran Packirisamy published an article in April 2019.
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Gino Rinaldi

1 shared publications

Ion Stiharu

1 shared publications

68
Publications
43
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1
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147
Citations
Publication Record
Distribution of Articles published per year 
(2007 - 2019)
Total number of journals
published in
 
35
 
Publications See all
Article 0 Reads 0 Citations Efficient Low Shear Flow-based Trapping of Biological Entities Ahmad Sohrabi Kashani, Muthukumaran Packirisamy Published: 02 April 2019
Scientific Reports, doi: 10.1038/s41598-019-41938-z
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Capturing cells or biological entities is an important and challenging step toward in-vitro studies of cells under a precisely controlled microscale environment. In this work, we have developed a compact and efficient microdevice for on-chip trapping of micro-sized particles. This hydrodynamics-based trapping system allows the isolation of polystyrene micro-particles with a shorter time while inducing a less hydrodynamic deformation and stress on the particles or cells both after and before trapping. A numerical simulation was carried out to design a hydrodynamic trapping mechanism and optimize the geometric and fluidic parameters affecting the trapping efficiency of the microfluidic network. By using the finite element analysis, the velocity field, pressure field, and hydrodynamic force on the micro particles were studied. Finally, a PDMS microfluidic device was fabricated to test the device’s ability to trap polystyrene microspheres. Computational fluid analysis and experimental testing showed a high trapping efficiency that is more than 90%. This microdevice can be used for single cell studies including their biological, physical and chemical characterization.
Article 1 Read 0 Citations Fluid load augmented micro balance Keshava Praveena Neriya Hegade, Muthukumaran Packirisamy, Ra... Published: 25 January 2019
Microsystem Technologies, doi: 10.1007/s00542-018-04289-9
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Article 0 Reads 0 Citations Perspective—Micro Photosynthetic Power Cells Hemanth Kumar Tanneru, Kiran Kuruvinashetti, Pragasen Pillay... Published: 18 January 2019
Journal of The Electrochemical Society, doi: 10.1149/2.0031909jes
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Micro-photosynthetic power cell (μPSC) is one of the emerging energy harvesting technologies which harvests energy using light (photosynthesis) and carbohydrate metabolism in dark (respiration) for low-power (mW range) applications. μPSC is a green technology that not only uses solar power and algae, but also provides power in both dark and light conditions. This perspective article provides state of the art of μPSC technology in terms of fabrication, mathematical modeling and energy harvesting circuit design. Currently, low power densities and high cost are the factors limiting μPSCs commercialization. Key aspects and methods to enhance the performance and decrease the cost are proposed in this paper.
Article 1 Read 0 Citations Perspective—Bio-Nano-Interaction in Treatment and Management of Cancer Ahmad Sohrabi Kashani, Simona Badilescu, Alisa Piekny, Muthu... Published: 20 December 2018
Journal of The Electrochemical Society, doi: 10.1149/2.0021909jes
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Due to the excellent biocompatibility of gold nanoparticles with human organism, they have great potentials for controlled drug delivery, cancer detection, cancer therapy, cancer management, and biomedical imaging. The unique optical and physiochemical properties of gold nanoparticles have made them a great candidate for intracellular diagnosis using surface-enhanced Raman microscopy and hyperspectral microscopy. These two techniques offer sensitive and non-invasive measurements. Gold nanoparticles also can be utilized to modulate the mechanobiological properties of cells, providing a platform to suppress the metastatic level of cells.
Article 0 Reads 0 Citations Study of Detection and Capture of Exosomes by Using the Morphologies of Ex Situ and In Situ Nanostructures Duraichelvan Raju, Srinivas Bathini, Simona Badilescu, Rodne... Published: 14 December 2018
Journal of The Electrochemical Society, doi: 10.1149/2.0011909jes
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Over the past few decades, fabrication of optimal nanostructures for detecting specific bio-entities remained an active area of research. It is well-known that the structure and the plasmonic properties of noble metal nanoparticles can be customized for specific applications such as biosensing, diagnosis, imaging, etc. by tuning the size and shape of the nanoparticles. Thus, by using the plasmonic property of noble metals, the detection at the nano-scale is possible by monitoring the shift of Localized Surface Plasmon Resonance (LSPR) band with respect to the changes in the dielectric constant of the surrounding medium. The present study is aimed to the evaluation of the quality and performance of two nano plasmonic platforms for detection and capture of exosomes.
Article 1 Read 0 Citations Polymer on Quartz Waveguide Sensing Platform for Enhanced Evanescent Fluorescence Spectroscopy Jalal Abdul-Hadi, Marc Andre Gauthier, Muthukumaran Packiris... Published: 01 December 2018
IEEE Photonics Journal, doi: 10.1109/jphot.2018.2876380
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