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Massimo De Vittorio      
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Massimo De Vittorio published an article in November 2018.
Top co-authors See all
Bernardo L. Sabatini

73 shared publications

Harvard Medical School

Ferruccio Pisanello

67 shared publications

Fondazione Istituto Italiano di Tecnologia

Francesco Rizzi

44 shared publications

Center for Biomolecular Nanotechnologies @UNILE, Istituto Italiano di Tecnologia, Arnesano (LE), I-73010, Italy

Massimo De Vittorio

36 shared publications

Istituto Italiano di Tecnologia (IIT), Center for Biomolecular Nanotechnologies, Via Barsanti, 73010 Arnesano, Italy

Leonardo Sileo

31 shared publications

Fondazione Istituto Italiano di Tecnologia

Publication Record
Distribution of Articles published per year 
(2012 - 2018)
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Publications See all
RAPID-COMMUNICATION 0 Reads 0 Citations Including Liquid Metal into Porous Elastomeric Films for Flexible and Enzyme-Free Glucose Fuel Cells: A Preliminary Eval... Denis Desmaële, Francesco La Malfa, Francesco Rizzi, Antonio... Published: 22 November 2018
Journal of Low Power Electronics and Applications, doi: 10.3390/jlpea8040045
DOI See at publisher website ABS Show/hide abstract
This communication introduces a new flexible elastomeric composite film, which can directly convert the chemical energy of glucose into electricity. The fabrication process is simple, and no specific equipment is required. Notably, the liquid metal Galinstan is exploited with a two-fold objective: (i) Galinstan particles are mixed with polydimethylsiloxane to obtain a highly conductive porous thick film scaffold; (ii) the presence of Galinstan in the composite film enables the direct growth of highly catalytic gold structures. As a first proof of concept, we demonstrate that when immersed in a 20 mM glucose solution, a 5 mm-long, 5 mm-wide and 2 mm-thick sample can generate a volumetric power density up to 3.6 mW·cm−3 at 7 mA·cm−3 and 0.51 V without using any enzymes.
PREPRINT-CONTENT 0 Reads 0 Citations Multipoint and large volume fiber photometry with a single tapered optical fiber implant Filippo Pisano, Marco Pisanello, Emanuela Maglie, Antonio Ba... Published: 29 October 2018
bioRxiv, doi: 10.1101/455766
DOI See at publisher website ABS Show/hide abstract
Techniques to monitor functional fluorescence signal from the brain are increasingly popular in the neuroscience community. However, most implementations are based on flat cleaved optical fibers (FFs) that can only interface with shallow tissue volumes adjacent to the fiber opening. To circumvent this limitation, we exploit modal properties of tapered optical fibers (TFs) to structure light collection over the wide optically active area of the fiber taper, providing an approach to efficiently and selectively collect light from the region(s) of interest. While being less invasive than FFs, TF probes can uniformly collect light over up to 2 mm of tissue and allow for multisite photometry along the taper. Furthermore, by micro-structuring the non-planar surface of the fiber taper, collection volumes from TFs can also be engineered arbitrarily in both shape and size. Owing to the abilities offered by these probes, we envision that TFs can set a novel, powerful paradigm in optically targeting not only the deep brain, but, more in general, any biological system or organ where light collection from the deep tissues is beneficial but challenging because of tissue scattering and absorption.
Article 0 Reads 0 Citations Tapered Fibers Combined With a Multi-Electrode Array for Optogenetics in Mouse Medial Prefrontal Cortex Leonardo Sileo, Sebastian H. Bitzenhofer, Barbara Spagnolo, ... Published: 26 October 2018
Frontiers in Neuroscience, doi: 10.3389/fnins.2018.00771
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Optogenetics offers many advantages in terms of cell-type specificity, allowing to investigate functional connectivity between different brain areas at high spatial and neural population selectivity. In order to obtain simultaneous optical control and electrical readout of neural activity, devices called “optrodes” are employed. They are typically composed of a linear array of microelectrodes integrated on a slender probe shafts combined with flat-cleaved optical fibers (FF) placed above the recording sites. However, due to tissue absorption and scattering, light delivered by the FF unevenly illuminates the region of interest. This issue is of particular relevance when cellular populations are disposed along the dorso-ventral axis, such as in medial prefrontal cortex (mPFC) where cortical layers are aligned vertically. The study presented here aims at using tapered optical fibers (TFs) in combination with a 16-electrode neural probe to better access neural populations distributed along the dorso-ventral axis in the mPFC of newborn mice, restricting light delivery over a specific portion of the cortical layer of interest. Half of the TF surface is coated with a reflecting metal blocking the light to enable light delivery from one side of the probe’s shaft only, with the probe base being designed to host the fiber without interfering with the wire-bonds that connect the recording sites to a printed circuit board. Monte-Carlo simulations have been implemented to define the relative TF-probe position and to identify the light intensity distribution above the recording sites. In vivo recordings indicate that simultaneous optical stimulation and electrical readout of neural activity in the mPFC benefit from the use of the engineered TF-based optrode in terms of a more uniform light distribution along the dorso-ventral axis and the possibility of restricting light delivery to a subset of electrical recording sites of interest.
Article 0 Reads 0 Citations Studying Cell Mechanobiology in 3D: The Two-Photon Lithography Approach Enrico Domenico Lemma, Barbara Spagnolo, Massimo De Vittorio... Published: 01 October 2018
Trends in Biotechnology, doi: 10.1016/j.tibtech.2018.09.008
DOI See at publisher website
Article 0 Reads 1 Citation Microfabrication of pH-responsive 3D hydrogel structures via two-photon polymerization of high-molecular-weight poly(eth... Elisa Scarpa, Enrico Domenico Lemma, Roberto Fiammengo, Mari... Published: 01 September 2018
Sensors and Actuators B: Chemical, doi: 10.1016/j.snb.2018.09.079
DOI See at publisher website
PREPRINT 0 Reads 0 Citations Analytical and empirical measurement of fiber photometry signal volume in brain tissue Marco Pisanello, Filippo Pisano, Minsuk Hyun, Emanuela Magli... Published: 09 July 2018