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Tim Wade   Dr.  Senior Scientist or Principal Investigator 
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Tim Wade published an article in October 2018.
Top co-authors See all
Alan Hubbard

572 shared publications

Centre for Glaciology, Department of Geography and Earth Sciences; Aberystwyth University; Aberystwyth UK

M. Potts

424 shared publications

University of Louisville, Louisville, KY

Peter Jensen

244 shared publications

National Food Institute; Technical University of Denmark; Kongens Lyngby Denmark

Stephen W. Marshall

226 shared publications

Department of Veteran Affairs Medical Center, Cleveland, OH

Peter Steen Jensen

194 shared publications

Neural Control of Movement Research Group, Department of Neuroscience and Pharmacology & Department of Nutrition, Exercise and Sport; University of Copenhagen; Copenhagen; Denmark

Publication Record
Distribution of Articles published per year 
(1998 - 2018)
Publications See all
Article 0 Reads 0 Citations Application of a salivary immunoassay in a prospective community study of waterborne infections Andrey I. Egorov, Shannon M. Griffin, Honorine D. Ward, Kevi... Published: 01 October 2018
Water Research, doi: 10.1016/j.watres.2018.05.030
DOI See at publisher website
Article 5 Reads 0 Citations Asymptomatic norovirus infection associated with swimming at a tropical beach: A prospective cohort study Timothy J. Wade, Swinburne A. J. Augustine, Shannon M. Griff... Published: 28 March 2018
PLOS ONE, doi: 10.1371/journal.pone.0195056
DOI See at publisher website
ABS Show/hide abstract
Swimming in fecally-contaminated waterbodies can result in gastrointestinal infections. However, the pathogenic microorganisms responsible are not well understood because sporadic cases of illness are not reported completely, exposure information is often not collected, and epidemiology studies rely on self-reported symptoms. Noroviruses are considered a likely cause because they are found in high densities in sewage, resistant to wastewater treatment and survive in the environment. In this study, saliva samples were collected from subjects at a beach in Puerto Rico and tested for evidence of norovirus-specific IgG responses as an indicator of incident norovirus infection. Saliva samples were collected from 1298 participants using an oral swab. Samples were collected on the day of the beach visit (S1); after 10–12 days (S2); and after three weeks (S3). Saliva was tested for IgG responses to GI.1 and GII.4 noroviruses using a microsphere based multiplex salivary immunoassay. Immunoconversion was defined as a four-fold increase in median fluorescence intensity (MFI) from S1 to S2 with the S3 sample at least three times above the S1 MFI. Thirty-four subjects (2.6%) immunoconverted to GI.1 or GII.4 norovirus. Swimmers who immersed their head in water had a higher rate of immunoconversion (3.4%), compared to either non-swimmers (0.0%, p = 0.003) or waders and non-swimmers combined (0.4%, Odds Ratio: 5.07, 95% Confidence Interval:1.48–17.00). Immunoconversion was not associated with gastrointestinal symptoms. This is the first study to demonstrate an association between swimming at a beach impacted by fecal contamination and asymptomatic norovirus infection. The findings implicate recreational water as potentially important transmission pathway for norovirus infection.
Article 4 Reads 1 Citation Waterborne disease outbreaks associated with environmental and undetermined exposures to water - United States, 2013-201... R. Paul McClung, David M. Roth, Marissa Vigar, Virginia A. R... Published: 21 December 2017
American Journal of Transplantation, doi: 10.1111/ajt.14607
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Article 3 Reads 0 Citations Erratum: “Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Dat... Jyotsna S. Jagai, Stephanie DeFlorio-Barker, Cynthia J. Lin,... Published: 21 December 2017
Environmental Health Perspectives, doi: 10.1289/ehp3143
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Article 3 Reads 0 Citations Child environmental exposures to water and sand at the beach: Findings from studies of over 68,000 subjects at 12 beache... Stephanie DeFlorio-Barker, Benjamin F Arnold, Elizabeth A Sa... Published: 08 November 2017
Journal of Exposure Science & Environmental Epidemiology, doi: 10.1038/jes.2017.23
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Article 3 Reads 0 Citations Extreme precipitation and emergency room visits for influenza in Massachusetts: a case-crossover analysis. Genee S Smith, Kyle P Messier, James L Crooks, Timothy J Wad... Published: 17 October 2017
Environmental Health, doi: 10.1186/s12940-017-0312-7
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ABS Show/hide abstract
Influenza peaks during the wintertime in temperate regions and during the annual rainy season in tropical regions - however reasons for the observed differences in disease ecology are poorly understood. We hypothesize that episodes of extreme precipitation also result in increased influenza in the Northeastern United States, but this association is not readily apparent, as no defined 'rainy season' occurs. Our objective was to evaluate the association between extreme precipitation (≥ 99th percentile) events and risk of emergency room (ER) visit for influenza in Massachusetts during 2002-2008.