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Josergio Zaragoza  - - - 
Top co-authors
Prashanth Asuri

13 shared publications

Department of Bioengineering; Santa Clara University; Santa Clara California USA

James Thomin

1 shared publications

Department of General Sciences, Northwest Florida State College, Niceville, FL 32578, USA

Marcus Kraus

1 shared publications

Department of Bioengineering, Santa Clara University, Santa Clara, CA 95053, USA;(J.Z.);(S.F.);(M.K.)

Scott Fukuoka

1 shared publications

Department of Bioengineering, Santa Clara University, Santa Clara, CA 95053, USA;(J.Z.);(S.F.);(M.K.)

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Publication Record
Distribution of Articles published per year 
(2018)
Total number of journals
published in
 
2
 
Publications
Article 1 Read 0 Citations Exploring the Role of Nanoparticles in Enhancing Mechanical Properties of Hydrogel Nanocomposites Josergio Zaragoza, Scott Fukuoka, Marcus Kraus, James Thomin... Published: 29 October 2018
Nanomaterials, doi: 10.3390/nano8110882
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
Over the past few decades, research studies have established that the mechanical properties of hydrogels can be largely impacted by the addition of nanoparticles. However, the exact mechanisms behind such enhancements are not yet fully understood. To further explore the role of nanoparticles on the enhanced mechanical properties of hydrogel nanocomposites, we used chemically crosslinked polyacrylamide hydrogels incorporating silica nanoparticles as the model system. Rheological measurements indicate that nanoparticle-mediated increases in hydrogel elastic modulus can exceed the maximum modulus that can be obtained through purely chemical crosslinking. Moreover, the data reveal that nanoparticle, monomer, and chemical crosslinker concentrations can all play an important role on the nanoparticle mediated-enhancements in mechanical properties. These results also demonstrate a strong role for pseudo crosslinking facilitated by polymer–particle interactions on the observed enhancements in elastic moduli. Taken together, our work delves into the role of nanoparticles on enhancing hydrogel properties, which is vital to the development of hydrogel nanocomposites with a wide range of specific mechanical properties.
Article 312 Reads 0 Citations Exploring the Effects of Nanoparticle Incorporation on the Mechanical Properties of Hydrogels Josergio Zaragoza, Prashanth Asuri Published: 16 April 2018
Proceedings, doi: 10.3390/iocn_2018-1-05191
DOI See at publisher website ABS Show/hide abstract
Recent studies have expanded our understanding of the effects of nanoparticles on hydrogel mechanical properties. However, further studies are needed to validate the generality of these findings, as well as to determine the exact mechanisms behind the enhancements afforded by the incorporation of nanoparticles. In this study, we performed rotational rheological characterizations of chemically crosslinked poly(acrylamide) hydrogels incorporating silica nanoparticles to better understand the role of nanoparticles on the enhanced properties of hydrogel nanocomposites. Our results indicate that incorporating nanoparticles can lead to enhancements in hydrogel elastic moduli greater than the maxima obtainable through purely chemical crosslinking. Moreover, we find that the increases in elastic moduli due to the addition of nanoparticles not only depend on particle concentration, but also on the monomer and chemical crosslinker concentration. Finally, our data indicates a strong role for pseudo-crosslinking mediated by noncovalent interactions between the nanoparticles and hydrogel polymers on the observed reinforcements. Collectively, our results shed further insight into the role of nanoparticles on enhancements of mechanical properties of hydrogels and may thereby facilitate engineering specific mechanical properties in a wide range of hydrogel nanocomposite systems.
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