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Byeong-Il Lee  - - - 
Top co-authors See all
Wei-Bor Tsai

120 shared publications

Department of Chemical Engineering, National Taiwan University, No. 1, Roosevelt Rd., Sec. 4, Taipei 106, Taiwan

Seok-Ki Kim

79 shared publications

Department of Nuclear Medicine

Saji Uthaman

41 shared publications

Department of Polymer Science and Engineering, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea

Joo Beom Eom

33 shared publications

Korea Photonics Technology Institute, Gwangju, 500-460, Korea (the Republic of)

In Hee Shin

6 shared publications

Korea Photonics Technology Institute, Korea (the Republic of)

Publication Record
Distribution of Articles published per year 
(2010 - 2018)
Total number of journals
published in
Publications See all
Article 0 Reads 2 Citations A Lipophilic IR-780 Dye-Encapsulated Zwitterionic Polymer-Lipid Micellar Nanoparticle for Enhanced Photothermal Therapy ... Santhosh Kalash Rajendrakumar, Ning-Chu Chang, Adityanarayan... Published: 13 April 2018
International Journal of Molecular Sciences, doi: 10.3390/ijms19041189
DOI See at publisher website PubMed View at PubMed ABS Show/hide abstract
To prolong blood circulation and avoid the triggering of immune responses, nanoparticles in the bloodstream require conjugation with polyethylene glycol (PEG). However, PEGylation hinders the interaction between the nanoparticles and the tumor cells and therefore limits the applications of PEGylated nanoparticles for therapeutic drug delivery. To overcome this limitation, zwitterionic materials can be used to enhance the systemic blood circulation and tumor-specific delivery of hydrophobic agents such as IR-780 iodide dye for photothermal therapy. Herein, we developed micellar nanoparticles using the amphiphilic homopolymer poly(12-(methacryloyloxy)dodecyl phosphorylcholine) (PCB-lipid) synthesized via reversible addition–fragmentation chain transfer (RAFT) polymerization. The PCB-lipid can self-assemble into micelles and encapsulate IR-780 dye (PCB-lipid–IR-780). Our results demonstrated that PCB-lipid–IR-780 nanoparticle (NP) exhibited low cytotoxicity and remarkable photothermal cytotoxicity to cervical cancer cells (TC-1) upon near-infrared (NIR) laser irradiation. The biodistribution of PCB-lipid–IR-780 showed higher accumulation of PCB-lipid–IR-780 than that of free IR-780 in the TC-1 tumor. Furthermore, following NIR laser irradiation of the tumor region, the PCB-lipid–IR-780 accumulated in the tumor facilitated enhanced tumor ablation and subsequent tumor regression in the TC-1 xenograft model. Hence, these zwitterionic polymer-lipid hybrid micellar nanoparticles show great potential for cancer theranostics and might be beneficial for clinical applications.
Article 0 Reads 2 Citations Dual-stimuli-responsive albumin-polyplex nanoassembly for spatially controlled gene release in metastatic breast cancer Santhosh Kalash Rajendrakumar, Kondareddy Cherukula, Hyeong ... Published: 01 April 2018
Journal of Controlled Release, doi: 10.1016/j.jconrel.2018.02.039
DOI See at publisher website
Article 0 Reads 2 Citations IR 780-loaded hyaluronic acid micelles for enhanced tumor-targeted photothermal therapy Saji Uthaman, Ansuja Pulickal Mathew, Hyeong Ju Park, Byeong... Published: 01 February 2018
Carbohydrate Polymers, doi: 10.1016/j.carbpol.2017.10.033
DOI See at publisher website
Article 0 Reads 0 Citations Effect of multi-wavelength irradiation on color characterization with light-emitting diodes (LEDs) Hyeong Ju Park, Woosub Song, Byeong-Il Lee, Hyejin Kim, Hyun... Published: 16 June 2017
Journal of the Korean Physical Society, doi: 10.3938/jkps.70.1011
DOI See at publisher website
Article 0 Reads 0 Citations Application of double-layered skin phantoms for optical flow imaging during laser tattoo treatments Byeong-Il Lee, Woosub Song, Hyejin Kim, Hyun Wook Kang Published: 07 May 2016
Journal of the Korean Physical Society, doi: 10.3938/jkps.68.1137
DOI See at publisher website
Article 0 Reads 2 Citations 3D printing-assisted fabrication of double-layered optical tissue phantoms for laser tattoo treatments Hanna Kim, Nguyen Trung Hau, Yu‐Gyeong Chae, Byeong‐Il Lee, ... Published: 08 January 2016
Lasers in Surgery and Medicine, doi: 10.1002/lsm.22469
DOI See at publisher website PubMed View at PubMed