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Cells Webinar | MicroRNAs in Cancer: From Molecular Mechanisms to Applications in Diagnostic and Therapeutic Opportunities

25 Jul 2023, 18:00 (CEST)

MicroRNA, Targeting, Tumor
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Webinar Content

On Tuesday, 25 July 2023, MDPI and the Journal Cells organized a webinar on “MicroRNAs in Cancer: From Molecular Mechanisms to Applications in Diagnostic and Therapeutic Opportunities”.

The introduction was led by the Chair of the webinar, Dr. Tohru Yamada, of the Department of Surgery, University of Illinois College of Medicine. His research interests include the discovery and development of a new class of peptide-based carriers and anticancer agents on the basis of molecular biology, protein/peptide chemistry, cell biology, and basic and translational cancer biology.

The first speaker was Dr. Jiemei Wang of the Department of Pharmaceutical Sciences, Wayne State University. The title of her presentation was “Targeting microRNA in tissue repair and regeneration”. Dr. Wang discussed the role of miRNAs in angiogenesis. The second speaker was Dr. Jun Chung of the Department of Pathology, Stony Brook Medicine. The title of his presentation was “Sensitization of Triple Negative Breast Cancers to PARP inhibitors by chemically modified micro-RNA 489”. He discussed the biological functions of chemically modified miRNA in drug-resistant breast cancer cells.

A Q&A session mediated by the Chair was held at the end of the webinar to answer any questions submitted by the live online audience and to further the connections and discussion between the panelists.

In this section, you will find the recordings of this webinar to watch, re-watch and share with your colleagues!

Event Chairs

Department of Surgery, College of Medicine, University of Illinois at Chicago, USA

DETAILS
Bio
Dr. Tohru Yamada is an Assistant Professor in the Department of Surgery, Division of Surgical Oncology at the University of Illinois, College of Medicine. Dr. Yamada was a Post-Doctoral Fellow in the school, Department of Microbiology Immunology. He received his B.S., M.S. and Ph.D. in Biotechnology from Tokyo Institute of Technology. His research interests and expertise are the discovery and development of new class of peptide-based anticancer agents (e.g., miRNA) and carriers for imaging agent targeting cancers on the basis of molecular biology, protein/peptide chemistry, cell biology and cancer biology.

Invited Speakers

Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, USA

DETAILS
Bio
Dr. Wang graduated from Sun Yat-Sen University in China with her MD and PhD degrees in 2004 and 2009, majoring in Cardiology, then finished her American Heart Associate Postdoctoral fellowship at the University of Pittsburgh in 2012. She started her tenure-track faculty position at Wayne State University after two years of research faculty position in the same institute and was granted tenure in 2021. She has delineated a series of research focusing on defining the molecular mechanisms essential to endothelial dysfunction and neovascularization in cardiovascular and metabolic disorders. An important aspect of her research is to develop new therapeutics to prevent/cure disrupted angiogenesis during tissue repair. Currently, she is the PI on two NIDDK R01 grants studying the molecular mechanisms of diabetic wound healing with a focus on stress signaling, microRNAs, and post-transcriptional regulatory networks. So far, her research findings have led to the original research of 42 original research papers in reputable journals, such as PNAS, Science Signaling, Diabetes, Hypertension, Molecular Therapy Nucleoid Acid, etc. Her publications can be found at NCBI: https://www.ncbi.nlm.nih.gov/myncbi/jie-mei.wang.1/bibliography/public/

Department of Pathology, Stony Brook University School of Medicine, Stony Brook, New York, USA

DETAILS
Bio
Yonsei University, Korea (BS, Biochemistry), Washington University School of Medicine, St.Louis, MO (Ph.D.), Harvard Medical School (postdoc, Pathology), Stony Brook University School of Medicine, Stony Brook, New York (Associate Professor, Pathology).

Program

Speaker/Presentation

Time in CDT

Time in CEST

Dr. Tohru Yamada
Chair Introduction

11:00–11:10 a.m.

6:00–6:10 p.m.

Dr. Jiemei Wang (Speaker 1)
Targeting microRNA in tissue repair and regeneration

11:10–11:30 a.m.

6:10–6:30 p.m.

Dr. Jun Chung (Speaker 2)
Sensitization of Triple Negative Breast Cancers to PARP inhibitors by chemically modified micro-RNA 489

11:30–11:50 a.m.

6:30–6:50 p.m.

Q&A Session

11:50–12:05 p.m.

6:50–7:05 p.m.

Closing of Webinar
Dr. Tohru Yamada (Chair)

12:05–12:10 p.m.

7:05–7:30 p.m.

Sponsors and Partners

Organizers

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