
Women are up to three times more likely than males to develop multiple sclerosis (MS), a chronic immune-mediated, inflammatory, and degenerative disease of the central nervous system. It was recommended that women with multiple sclerosis refrain from getting pregnant around fifty years ago. Since then, epidemiological studies have provided evidence that pregnancies have no effect on the course of the disease and that a mother’s MS condition has no detrimental effects on the development of her child. For women with MS, there are other unknowns to take into account, such as the possibility that their capacity to care for their children may be impacted by acute relapses and incapacity in the future. MS immunotherapies and medical knowledge about pregnancy and fertility are always changing, but treatment recommendations in this field should also be updated and altered on a regular basis. A multidisciplinary approach to MS is essential since, crucially, the longevity of individuals with MS is growing. Cardiovascular diseases (CVDs) may be linked to MS; however, this connection has received little attention. Additionally, MS patients have a greater frequency of cardiovascular risk factors. However, diseases such as Takotsubo syndrome are uncommon side effects of multiple sclerosis. It is also intriguing how myocarditis and MS are similar. Last but not least, heart toxicity is a common side effect of MS medications. This webinar's objective is to present an update on pregnancy-related concerns for women with MS, including suggestions for counseling, general care, the use of DMTs before, during, and after pregnancy, and DMTs' effects on nursing. In order to stimulate more clinical and pre-clinical research on the subject, the second section of this webinar attempts to give an overview of cardiovascular problems in MS and how they are managed.
Date: 20 May, 2025
Time: 6:00 PM CEST | 7:00 PM EEDT
Webinar ID: 827 6230 9752
Webinar Secretariat: journal.webinar@mdpi.com


We are grateful to organized the successful webinar entitled:''Challenges in the Clinical Practice of Multiple Sclerosis'' with esteemed guest speakers Dr Gabriela Mihailescu and Dr Elias Gialafos.Dr Gabriela Mihailescu updated the clinical guidelines on pregnancy and post partum period for women with MS. Dr Elias Gialafos covered insights from studies linking key inflammation to autoimmune mechanisms underlying cardiological dysfunction in MS, and the impact of environmental factors in cardiovascular disease pathogenesis. Overall, their lectures offered a comprehensive look at how pregnancy and cardiological issues are challenges for MS and potential therapeutic strategies.
The webinar was hosted via Zoom and required registration to attend. The full recording can be found below. In order to learn about future webinars, you can sign up to our newsletter by clicking “Subscribe” at the top of the page.