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Non-Coding RNA Webinar | Sequence-Based Small Molecule Targeting of RNA

Part of the Non-Coding RNA Journal Webinar series
7 July 2026, 16:00 (CEST)

Registration Deadline
7 July 2026

RNA Structure, Chemical Biology, Medicinal Chemistry, Small Molecules
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Welcome from the Chair

20th ncRNA Webinar

Sequence-Based Small Molecule Targeting of RNA

The Non-Coding RNA journal webinar is open to all who enjoy doing any type of research on the topic of non-coding transcripts or are passionate about learning about this exciting and competitive research area. The webinar speakers will present new findings from basic to translational research.

Prof. Disney’s webinar will be about RNA targeting by small molecules.He will show us how RNA sequence can guide the design of small molecules that bind disease-causing RNAs with selectivity. By combining this with target-engagement and RNA-degradation strategies, these compounds can either change RNA function or remove harmful RNAs from cells. This creates a practical path to make medicines for diseases driven by RNA.

Date: 7 July 2026
Time: 4:00 pm CEST | 10:00 am EDT
Webinar ID: 835 6300 2627
Webinar Secretariat: journal.webinar@mdpi.com

Event Chairs

Institute of Clinical Physiology (IFC), National Research Council (CNR) and Oncogenomics Unit, Core Research Laboratory (CRL), Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO)

Introduction
Bio
Dr. Poliseno graduated in Biological Sciences in 2000 and got her PhD in Molecular Biotechnology in 2004, both at University of Pisa, Italy. In 2006, she moved to the US, where she became a post-doctoral fellow in the laboratory of Prof. Pier Paolo Pandolfi, first at MSKCC in New York and then at BIDMC-HMS in Boston. In 2009, she started a second post-doc in the lab of Prof. Iman Osman at NYU. In 2012, she was appointed as Principal Investigator of the Oncogenomics Unit of ITT (now ISPRO) and in 2016 she became Staff Scientist at the Institute of Clinical Physiology of the National Research Council in Pisa, Italy, where her lab is located. Throughout her scientific career, Dr. Poliseno’s research interests have mostly revolved around non-coding RNAs (microRNAs, pseudogenes, ceRNAs) in cancer. Currently, the activities of the Poliseno lab are focused on the coding and non-coding regulatory networks of BRAFV600E isoforms in melanoma. They are also developing strategies for the selective delivery of drug combinations inside cancer cells, exploiting the attenuated bacterium Listeria monocytogenes.

Invited Speakers

Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, United States

Introduction
Bio
Matthew Disney, PhD, is Institute Professor and Chair of the Department of Chemistry at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology and Founding Director of the Center for RNA Genomic Medicine. His research focuses on designing small molecules that target RNA to understand and treat genetic diseases. His laboratory has pioneered approaches to identify drug-like small molecules that bind structured RNAs and modulate their biology, including RNA degradation and splicing. Dr. Disney has published extensively, trained more than 150 scientists, founded biotechnology companies, and received several honors, including the NIH Director’s Pioneer Award, the Raymond and Beverly Sackler International Prize in the Physical Sciences, the ACS David W. Robertson Award in Medicinal Chemistry, the ACS Eli Lilly Award in Biological Chemistry, and the Camille and Henry Dreyfus Teacher-Scholar Award.

Registration

This is a FREE webinar. After registering, you will receive a confirmation email containing information on how to join the webinar.  Registrations with academic institutional email addresses will be prioritized.

Certificates of attendance will be delivered to those who attend the live webinar.

Can’t attend? Register anyway and we’ll let you know when the recording is available to watch.

Program

Speaker/Presentation Time in CEST Time in EDT

Chair Introduction

Dr. Laura Poliseno

4:00 - 4:10 pm 10:00 - 10:10 am

Sequence-Based Small Molecule Targeting of RNA

Dr. Matthew Disney

4:10 - 4:40 pm 10:10 - 10:40 am

Q&A Session

4:40 - 4:50 pm 10:40 - 10:50 am

Closing of Webinar

Dr. Laura Poliseno

4:50 - 5:00 pm 10:50 - 11:00 am

Sponsors and Partners

Organizers

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