The 3rd International Electronic Conference on Biosensors
Part of the International Electronic Conference on Biosensors series
8–21 May 2023
Wearable Biosensors, Implantable Biosensors, Labonachip, POCT, Green Chemistry, Bionanotechnology and Nanomaterials, Microfluidics
- Go to the Sessions
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- A. Artificial Intelligence in Biosensors
- B. Ingestible, Implantable and Wearable Biosensors
- C. Smartphone-based Biosensors
- D. The Evolution of Biological Recognition Elements in Biosensors
- E. Microfabrication and Printing Techniques in Biosensors
- F. Nanomaterials and Smart Surfaces in Biosensors
- G. Technological Advancements in Biosensor Actuators
- H. Paper-based Biosensors
- I. Optical and Photonic Biosensors
- Event Details
IECB 2023 is closed. Thank you for your participation.
The winners of the IECB 2023 awards have been announced HERE ! Congratulations!
The accepted papers will be published as one dedicated volume in the MDPI journal Engineering Proceedings (indexed within Scopus, ISSN 2673-4591). Publication of proceedings paper is free of charge.
All participants of IECB 2023 are also welcomed to submit the extended work to the Biosensors(ISSN 2079-6374; IF 5.743) conference special issue with a 20% discount on the article processing charge.
Welcome from the Chairs
Dear Biosensors Community,
It is our pleasure to invite you to join the 3rd International Electronic Conference on Biosensors (IECB 2023), which will be hosted online from 8 to 21 May 2023 at IECB2023.sciforum.net.
Biosensors currently have an enormous range of applications due to their simplicity, low cost and precision, improving our overall quality of life with uses in, for example, environmental monitoring, disease detection, food safety, defense, drug discovery, and many others.
The aim of this online conference is to gather worldwide well-known experts currently working in biosensors and to provide an online forum for sharing and exchanging knowledge.
Particular attention will be given to young scientists approaching the world of biosensors, with a conference session dedicated specifically to this demographic.
Throughout the event we aim to cover—among others—the following topics:
1. Artificial intelligence in biosensors;
2. Ingestible, implantable and wearable biosensors;
3. Smartphone-based biosensors;
4. The evolution of biological recognition elements in biosensors;
5. Microfabrication and printing techniques in biosensors;
6. Nanomaterials and smart surfaces in biosensors;
7. Technological advancements in biosensor actuators.
We hope you will join us in presenting your work at IECB 2023 and be part of this stimulating online experience.
Kind regards,
Professor Giovanna Marrazza and Dr. Sara Tombelli
The chairs of the 3rd International Electronic Conference on Biosensors.
Event Chairs
Department of Chemistry “Ugo Schiff”, University of Florence, Italy
Dr. Giovanna Marrazza is the Editor-in-Chief of Biosensors, an open access journal devoted to studies related to the science and technology of biosensors and biosensing. Dr. Giovanna Marrazza has served as Associate Professor in Analytical Chemistry at Department of Chemistry “Ugo Schiff” of the University of Florence since 2001 and is currently President of the study course for the Chemistry degree at this University. She is a distinguished Visiting Professor at the Faculty of Pharmacy “Iuliu Haţieganu” University of Medicine & Pharmacy, Cluj-Napoca (Romania) and member of the steering board of Italian Sensors and Microsystems Group (AISEM). Marrazza’s research focuses on electrochemical, piezoelectric, and optical nano(bio)sensors based on enzymes, antibodies, bacteria, DNA, molecularly imprinted polymers, and aptamers. Her research is focused on new biosensing principles containing nanomaterials and modified interfaces, design procedures suitable for biosensor devices as flow injection analysis, microflow systems, thick-film technology, and nanodispensing technologies. She has co-authored more than 140 papers in leading international journals in addition to numerous book chapters.
Tombelli, Sara graduated in Chemistry at the University of Florence, Italy, in 1996. She received the PhD in Environmental Sciences with full marks in 2001 at the Department of Chemistry (Florence, Italy). She is now senior researcher at the Institute of Applied Physics (IFAC-CNR) in Florence, Italy. Her research activity is focused on analytical chemistry, biosensor development and surface modifications with bio-molecules, such as antibodies, enzymes, aptamers and nucleic acid probes. She has also experience in intracellular nanosensors and nanoparticle manipulation. On the above topics she has contributed more than 130 publications on international refereed journals, books and conference proceedings (H-index=38, Scopus). She participated in several European Projects (Nanodem, Hemospec, Careman, Gapogrowth) and in other national and international projects. She is now research unit scientific leader in the national project PRIN “Development of novel DNA-based analytical platforms for the rapid, point-of-use quantification of multiple hidden allergens in food samples”. She has been reviewer and referee for the evaluation of international projects such as proposals under the ERC Ideas Specific Programme and the FET programme. She received the National Scientific Habilitation (ASN) as full and associate professor in Analytical Chemistry (Italian Ministry for Research).
Event Committee
Department of Bioengineering, University of California, USA
Dr. Jun Chen is currently an assistant professor in the Department of Bioengineering at the UCLA Samueli School of Engineering. His research focuses on nanotechnology and bioelectronics for energy, sensing, and therapeutic applications in the form of smart textiles, wearables, and body-area networks. He has published two books, and 230 journal articles, with 130 of them being the corresponding authors in Chemical Reviews(2), Chemical Society Reviews(2), Nature Materials(1), Nature Electronics(3), Nature Communications(2), Science Advances, Joule(3), Matter(6), Advanced Materials(10) and many others. His works have been highlighted by Nature and Science 7 times and covered by global mainstream media more than 1,200 times, including CNN, ABC, NBC, NPR, Newsweek, The Wall Street Journal, Reuters, and Scientific American. He has filed 14 U.S. patents, including one licensed. Dr. Chen has been selected as one of the world’s most influential researchers in the field of materials science by Web of Science. Among his many accolades are the Fellow of International Association of Advanced Materials, ACS PMSE Young Investigator Award, 30 Life Sciences Leaders To Watch by Informa, UCLA Society of Hellman Fellows Award, Okawa Foundation Research Award, Chem. Soc. Rev. Emerging Investigator Award, Advanced Materials Rising Star, ACS Nano Rising Stars Lectureship Award, IAAM Scientist Medal, 2020 Altmetric Top 100, Top 10 Science Stories of 2020 by Ontario Science Centre, Highly Cited Researchers 2021/2020/2019 in Web of Science, Frontiers in Chemistry Rising Stars, JMCA Emerging Investigator Award, Nanoscale Emerging Investigator Award, and many others. Beyond research, he is an associate editor of Biosensors and Bioelectronics, and Advisory/ Editorial Board Members of Matter, The Innovation, Nano-Micro Letters, Materials Today Energy, Cell Reports Physical Science, and Biomedical Technology.
Analytical Chemistry Department, Faculty of Pharmacy, "Iuliu Haţieganu" University of Medicine and Pharmacy 4, Romania
Dr. Cecilia Cristea is full professor of Analytical Chemistry in the Faculty of Pharmacy of the "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania. She also graduated the Faculty of Chemistry from Babes-Bolyai University Cluj-Napoca. After receiving her PhD in Chemistry from Rennes 1 University, France and Babes-Bolyai University Cluj-Napoca, Romania and her post doctoral research stays in Sherbrook University, Canada, her main field of interest changed from organic electrosynthesis to electrochemical and optical biosensors, screen printed electrodes design, immuno and aptasensors development for pharmaceutical and biomedical analysis, molecularly imprinted polymers based sensors, wearable sensors, targeted drug delivery by electrodriven techniques, hyphenated techniques.
School of Public Health, Hengyang Medical School, University of South China, China
Dr. Xiangheng Niu is now working as a professor in University of South China, and he is interested in the design of novel nanozymes and their emerging applications in sensors and biosensors, especially in food, environmental, clinical, and biomedical analyses. He is the Young Editorial Board Member and Guest Editor of several journals including Biosensors. He has published over 120 peer-review publications in journals including TrAC Trends Anal. Chem., Anal. Chem., Biosens. Bioelectron., Small, J. Hazard. Mater., Sens. Actuators B Chem., and Chem. Eng. J.
Department of Engineering Science and Mechanics, The Pennsylvania State University, USA
Huanyu Cheng is the James L. Henderson, Jr. Memorial Associate Professor of Engineering Science and Mechanics at Penn State University. His research group focuses on the design, fabrication, and application of the standalone stretchable device platform. Larry has co-authored more than 120 publications with total citations >15,000 according to Google Scholar. His work has been recognized through the reception of numerous awards, including the Humboldt Research Fellowship for Experienced Researchers, 2022 Minerals, Metals & Materials Society (TMS) Functional Materials Division (FMD) Young Leaders Professional Development Award, 2021 NIH Trailblazer Award, MIT Technology Review Innovators Under 35 (TR35 China) in 2021, 2021 Scialog Fellow in Advancing BioImaging, 2021 Frontiers of Materials Award from TMS, Forbes 30 Under 30 in 2017, among others. He also serves as the associate editor for 7 journals and reviewer for > 200 journals.
In 1998 he was awarded a Ph.D. in engineering from The University of Tokyo for his research development on an automatic chemiluminescence flow injection analysis system (ACL-FIA) biosensors for phosphate ion in natural water. Currently, he is an assistant professor at Tokyo University of Technology. To this day, he has developed many biosensor chip designs, mainly for self-monitoring of blood glucose (SMBG). He has applied for 173 patents, 63 of which have been registered in Japan. As the other works in clinical fields, he also developed a self-sterilizing lancet, needle-integrated SMBG biosensor chips, a micromachined CL-FIA biosensor, and an enzyme-chromogenic surface plasmon resonance biosensor probe, etc. As the works in food analyses, he developed ferricyanide chronoamperometric total antioxidant capacity assay methods for vegetables and green tea, and a yeast double mediator method for alcohol. As the works in environmental fields, he supported the practical use of agricultural soil microbial biosensor “Soil Dock™” for the first time in the world. As the other works in the environmental fields, he studied a new concept toxicity assay for simultaneous qualitative and quantitative analyses based on multiple indexes from the wave shape of damped metabolic oscillation induced in living yeast cells. He also developed yeast double mediator biochips for BOD, spectrophotometric BOD methods, and a chemiluminometric BOD method. As a guest editor of Biosensors, he published the first special issue of “Dedication to the TUT President Dr. Isao Karube: Microbial Biosensors" in 2021 and will be published the second special issue of “Microbial Biosensors for Environmental Monitoring" in 2022.
Professor Michael Thompson obtained his undergraduate degree from the University of Wales, UK and his PhD in analytical chemistry from McMaster University. Following a period as Science Research Council PDF at Swansea University he was appointed Lecturer in Instrumental Analysis at Loughborough University. He then moved to the University of Toronto where he is now Professor of Bioanalytical Chemistry. He has held a number of distinguished research posts including the Leverhulme Fellowship at the University of Durham and the Science Foundation Ireland E.T.S Walton Research Fellowship at the Tyndall National Institute, Cork City. He is recognized internationally for his pioneering work over many years in the area of research into new biosensor technologies and the surface chemistry of biochemical and biological entities. He has made major contributions to the label-free detection of immunochemical and nucleic acid interactions and surface behavior of cells using ultra high frequency acoustic wave physics. Recently, scanning Kelvin nanoprobe detection has been introduced which offers the multiplexed detection of biochemical phenomena. Thompson has served on the Editorial Boards of a number of major international journals including Analytical Chemistry, The Analyst, Talanta, Analytica Chimica Acta and Biosensors and Bioelectronics. He is currently Editor-in-Chief of the monograph series “Detection Science” for the Royal Society of Chemistry, UK. He has been awarded many prestigious international prizes for his research including The Robert Boyle Gold Medal of the Royal Society of Chemistry, E.W.R. Steacie Award of the Chemical Society of Canada, the Theophilus Redwood Award of the Royal Society of Chemistry and the Fisher Scientific Award in Analytical Chemistry of the Chemical Society of Canada. He was made a Fellow of the Royal Society of Canada in 1999.
Benoît PIRO, 49 y.o., H-factor 39, 4800+ citations, is professor in Chemistry, Université de Paris, France, laboratory ITODYS associated to CNRS. He developed biosensors based on original electrochemical transduction schemes such as "reagentless" and "signal-on", directed to DNA, miRNA, proteins, peptides, antibodies, organic pollutants... and participated in their economic valorization (patents, private contracts). He is developing activities related to inkjet-printing in general and printed organic electronics. This technique, applied to electrolyte-gated organic FETs and electrochemical transistors adapted to work in aqueous media, paves the way for mass production and applications in the medical and environmental fields. He is a member of the French Printed Organic Electronics Association, administrator of the French Group of Bioelectrochemistry., and Section Editor-in-Chief of Biosensors and Bioelectronic Devices, MDPI.
Department of Chemistry & Biomolecular Science, Clarkson University, USA
Evgeny Katz received his Ph.D. in Chemistry from Frumkin Institute of Electrochemistry (Moscow), Russian Academy of Sciences, in 1983. He was a senior researcher in the Institute of Photosynthesis, Russian Academy of Sciences, in 1983-1991. In 1992-1993 he performed research at München Technische Universität (Germany) as a Humboldt fellow. Later, in 1993-2006, Dr. Katz was a Research Associate Professor at the Hebrew University of Jerusalem. From 2006 he is Milton Kerker Chaired Professor at the Department of Chemistry and Biomolecular Science, Clarkson University, NY (USA). He has (co)authored over 520 papers in peer-reviewed journals/books with the total citation more than 40,000 (Hirsch-index 93) and holds more than 20 international patents. He edited/wrote nine books on different topics, including bioelectronics, molecular and biomolecular computing, implantable bioelectronics and forensic science. He was an Editor-in-Chief for IEEE Sensors Journal (2009-2012). Presently he is an Associate Editor of Electrochemical Science Advances (Wiley), Applied Research (Wiley) and a member of editorial boards of many other journals. His scientific interests are in the broad areas of bioelectronics, biosensors, biofuel cells, and biomolecular information processing (biocomputing).
Center for Applied Physics and Advanced Technology of the National Autonomous University of Mexico (UNAM)
Eden Morales-Narváez is currently the Head of the Biophotonic Nanosensors Laboratory at the Center for Applied Physics and Advanced Technology of the National Autonomous University of Mexico (Universidad Nacional Autónoma de México, UNAM). He received a degree in bionics engineering from the National Polytechnic Institute of Mexico in 2006 and his Ph.D. in biomedical engineering from the Polytechnic University of Catalonia, Spain in 2013. He was a Postdoctoral Researcher at Catalan Institute of Nanoscience and Nanotechnology and started his independent career in late 2016 at the Center for Research in Optics (Mexico). His research is focused on the development and application of novel (bio)sensing platforms, particularly using nanophotonics at the cutting-edge. In general, he is interested in green technologies, smart materials, integrated biosensors, wearable devices, flexible photonics, and healthcare 4.0/5.0. He is a member of several editorial boards including Biosensors, ACS Analytical Chemistry, Biosensors & Bioelectronics X, JPhys Photonics and Green Analytical Chemistry, among others. He has also been recognized as an Emerging Leader 2020 by IOP Publishing.
Department of Chemical Sciences and Technologies, Università degli Studi di Roma Tor Vergata, Italy
Prof. Danila Moscone is Full Professor in Analytical Chemistry at the Chemical and Technology Department of the University of Rome “Tor Vergata”. She is involved for more than thirty years in the field of biosensors and is expert in electrochemical biosensor assembling, their analytical evaluation and application for solving real analytical problems. Her more recent interests concern sensors modification with nanomaterials and the realization of “all-in-one” paper-based electrochemical and optical devices and wearable (bio)sensors. She is a member of ACS and SCI, and Editor of Biosensors and Bioelectronics. Her scientific activity is summarised in 223 papers and chapters on books on International and National scientific journals, 5 patents and more than 500 oral and poster presentations at scientific meetings. Her actual H-index is 59, with 9629 citations (2022 Aug, Scopus).
Center for Cellular and Molecular Diagnostics , School of Medicine, Tulane University, USA
Prof. Chenzhong Li is the professor of Biochemistry and Biomedical Engineering and the Deputy Director of the Center of Cellular and Molecular Diagnosis at Tulane University. Prior to joining Tulane in 2021, he was the Worlds Ahead Professor and the director of Nanobioengineering/Bioelectronics Core in the Department of Biomedical Engineering of Florida International University (Miami). He is the former program director of the National Science Foundation of USA to manage the Biosensing program nationwide. Dr. Li is an expert in bioinstrumentation and nanobiotechnology, specifically in the development of electrical and optical biosensors with an emphasis on diseases theranostics and tissue engineering. Dr. Li’s research interests includes organ on a chip, single cell analysis, point of care testings, DNA and Cell Electronics, wearable devices, as well as electron transfer study of various biomaterials. The impact of his work is documented in 17 granted patents, about 160 peer-reviewed journal papers, 2 books and 7 book chapters. Currently Dr. Li is the co-Editor in Chief of the flagship journal Biosensor and Bioelectronics, the Deputy Editor of journal of RESEARCH, and the associate editor of journal of Biosensors. Dr. Li is the elected fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the fellow member of National Academy of Inventors (NAI). In 2015, Dr. Li historically co-led and successfully developed two NSF Engineering Research Centers (ERCs)-PATHUP (The Precise Advanced Technologies and Health Systems for Underserved Populations, $ 50 million, 2017-2027) and CELLMET (Directed Multiscale Assembly of Cellular Metamaterials with Nanoscale Precision, $ 51 million, 2017-2027), and one NSF Research Traineeship (NRT) project called Nanomedicine Academy, which translate cutting-edge advances in nanotechnology and biomedical engineering into an education model for low-resource institutions.
Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Germany
Dr. Michael G. Weller is the Head of Division 1.5 Protein Analysis at the Federal Institute for Materials Research and Testing (BAM) in Berlin, Germany. He received his Ph.D. from the Technical University of Munich (TUM) in Analytical Chemistry. Subsequently, he joined the Division of Analytical Chemistry Research at Ciba-Geigy in Basel, Switzerland, for a postdoctoral stay. After leading a bioanalytical research group at TUM, he finished his habilitation in immunochemistry and now teaches bioanalytical subjects at Humboldt University Berlin. His research interests include many bioanalytical topics such as antibodies, immunoassays, biosensors, microarrays, affinity chromatography, monolithic materials, quantitative protein analysis, bioconjugation, lab-on-a-chip, and peptide libraries. Furthermore, he is engaged in the design, traceability, and quality control of bioreagents.
Department of Chemistry & Biomolecular Science, Clarkson University, USA
Oleh Smutok received his PhD from the Institute of Cell Biology, National Academy of Sciences (NAS) of Ukraine in 2007. In 2019 he obtained a D.Sc. degree (Habilitation) - the highest university degree in European countries. He was a Senior Researcher at the Department of Analytical Biotechnology, Institute of Cell Biology, NAS of Ukraine, Lviv, Ukraine (2013-2020) and Associate Professor in Department of Biology and Chemistry, Drohobych Ivan Franko State Pedagogical University, Drohobych, Ukraine (2017-2020). Starting from 2020, he is Research Assistant Professor in the Department of Chemistry & Biomolecular Science, Clarkson University, Potsdam, New York, USA. His professional Honors include the highest scientific Awards of Ukraine: State Prize of President of Ukraine for Young Scientists (2011); State Prize of the Government of Ukraine (2013); State Prize of Ukraine in the field of science and technology (2018). He has (co)authored over 90 papers in peer-reviewed journals/books including the high-level journals like: Nature Communications, Angewandte Chemie, Biosensor & Bioelectronics, etc. His current research interests are focused on the fields of Applied Enzymology, Nanotechnology, Electrochemistry, Analytical chemistry, Biosensorics.
School of Biological and Health Systems Engineering and Biodesign Center for Bioelectronics and Biosensors, Arizona State University, USA
Shaopeng Wang is an associate professor jointly appointment by School of Biological and Health Systems Engineering and Biodesign Center for Bioelectronics and Biosensors of Arizona State University. He had seven years industrial research experiences and was a research faculty at Biodesign Institute from 2008 to 2021. Dr. Wang’s research interest is in the development of biosensors and bioanalytical instrumentations based on optical and electrochemical sensing methods. Dr. Wang has received over $20 million USD extramural research funding over the past two decades. He has more than 130 peer reviewed journal publications, 4 book chapters and 5 issued patents, with a total citation over 8000 and an H-index of 46. He has published in top journals including Science, PNAS, Nature Methods, Natural Chemistry, Natural Nanotechnology, ACS Nano and Nano letters. Dr. Wang is the editorial board member of Biosensors.
Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), Spain
M.-Carmen Estévez received a Bachelor of Chemistry in 1998 from the University of Barcelona (UB, Spain) and obtained her M. Sc. (1999) and Ph.D. in Chemistry (UB, Spain) in 2005 focused on the development of immunochemical techniques for environmental monitoring. She performed a postdoctoral stay at the University of Florida (Dept. Chemistry, UF) between 2006 and 2008. She focused on nanobiotechnology applied to in-vitro diagnostics. Since 2009 she holds a Senior Researcher position in the Nanobiosensors and Bioanalytical Applications group at the Institut Català de Nanociència i Nanotecnologia (ICN2) and CSIC (Barcelona, Spain). Her main research interests focus on plasmonic and silicon photonics sensors, their integration in compact prototypes, and the development of biosensor-based applications to demonstrate their potential for real clinical, industrial, and/or environmental applications, aiming at transferring them to decentralized settings. She has co-authored more than 40 papers in leading journals in nanotechnology, analytical chemistry, biosensors, and optics. She is an active reviewer in ACS, Elsevier, RSC, and Wiley journals.
School of Aerospace, Transport and Manufacturing, Cranfield University, UK
Dr Iva Chianella is currently Senior Lecturer in Bio-sensors and Functional Polymers at Cranfield University. She is an experienced Scientist with a strong research track record on the development of affinity sensors/biosensors based on natural and artificial receptors for clinical, environmental, food, safety and industrial applications. After receiving her first degree in Chemistry from the University of Florence, and her PhD in Bioscience from Cranfield University, Dr Chianella was appointed as Lecturer in 2007 and as Senior Lecturer in 2020. She has co-authored around 60 peer-reviewed papers, 7 book chapters and 4 patents) in diagnostics and in novel polymeric materials and their use in several analytical systems. Dr Chianella main research interests are: i) development of chemical and biochemical sensors/nano-sensors for point-of-care and in-field applications; ii) synthesis of novel polymeric nanomaterials (e.g. Molecularly Imprinted Polymers Nanoparticles) for sensors and assays and other analytical system; iii) development and use of nanomaterials (e.g. iron oxide nanoparticles) for biomedical applications.
Plenary Speaker
Professor Sergey A. Piletsky
Department of Chemistry, University of Leicester, Leicester, UK
MIP Nanoparticles for Diagnostics and Imaging Applications
A leading expert on Molecular Imprinting and Biosensors. Sergey Piletsky is a Professor of Bioanalytical Chemistry and Research Director for School of Chemistry. Sergey has graduated from Kiev University in 1985 with a M.Sc. in Bioorganic Chemistry. In 1991 he received Ph.D. from Institute of Bioorganic Chemistry. Since 1992 he worked with world leading experts in biosensors such as Prof. Karube in Tokyo University, Prof. Wolfbeis in Regensburg University and Prof. Turner in Cranfield University. In 2002 Sergey became Professor of Polymer Chemistry and Head of Cranfield Biotechnology Centre. In 2013 Sergey has moved his group to the University of Leicester where he is working as a Research Director and Head of Leicester Biotechnology Group. For his scientific achievements, Sergey received number of awards such as JSPS, DFG and Leverhulme Fellowships, the award of the President of Ukraine, Royal Society Wolfson Research Merit Award, Silver Medal from Royal Society of Chemistry (Macro Group) for significant and substantial contribution to the development of polymer science, and DSc from Cranfield University. Sergey has published more than 400 papers and patent applications (H-index-84). The focus of Sergey’s work has been on molecularly imprinted polymers, driven by a practical need to find stable and generic alternatives to antibodies and natural receptors, as well as reducing the use of animals in antibody production. His research interests also include (i) Computational design and molecular modelling; (ii) Development of sensors and assays for clinical and environmental diagnostics; (iii) Nanoparticles for diagnostics and therapeutic applications. This work has been supported by 11 EU projects, grants from MRC and EPSRC (JREI), grants from HPA, FSA and Home Office, Department of Health, Wellcome Trust, (UK), NOAA (USA), and numerous grants from industry.
Keynote Speakers
Advancing Electroanalysis with the Use of Paper-Based Substrates
Stefano Cinti is an Associate Professor at the Department of Pharmacy, University of Naples “Federico II”. He obtained a Ph.D. in Chemical Sciences in 2016 in the group headed by Prof. Giuseppe Palleschi at the University of Rome “Tor Vergata”. He leads the uninanobiosensors Lab (uninanobiosensors.com) at University of Naples “Federico II”, and his research interests include the development of electrochemical sensors, paper-based devices, nanomotors, and nanomaterials. During his research activity, he had the opportunity to spend a period abroad in Finland, U.K., U.S., Germany, and Spain. He has published more than 65 papers in peer-reviewed journals, with an H-index of 30 and >3000 citations. Among all the prizes and certificates, in 2018 he was named Best Young Researcher in Bio-Analytical Chemistry, and in 2019 he was named Best Young Researcher in Analytical Chemistry (both by the Italian Chemical Society), and in 2021 he has been recognized as the World’s Top 2% Scientists. He is the coordinator of the Chemical Cultural Diffusion group of Italian Chemical Society. He is the Chair of AMYC-BIOMED, a multidisciplinary conference for young chemists in the biomedical sciences. He is very active in communicating science to nonspecialized audiences through TV shows, radio, and magazine.
Departamento de Química Física y Analítica Universidad de Oviedo, Spain
Electrochemical Detection of Circulating lncRNA for Cancer Diagnosis
Dr. María Jesús Lobo-Castañón holds a PhD in Chemistry and leads the Electroanalysis research group at the University of Oviedo in Spain. Since 2007 she is Full Professor in Analytical Chemistry at said University. Her research interests focus on the development of electrochemical sensors for clinical diagnosis and food analysis, using different molecular recognition elements, such as enzymes, DNA and aptamers. She is (co)author of over 130 articles in leading international journals and various book chapters in that field. Her H-index is 36, with a total citation over 4200 (2022 September, Scopus). All her written work is available on the group website: https://www.unioviedo.es/electroanalysis/
Institute of Physical and Theoretical Chemistry (IPTC), Eberhard Karls Universität Tübingen, Germany
The Future of Reflectometric Biosensing
Dr. Günther Proll studied Technical Biology at the University of Stuttgart, Germany with a specialization in Physical Chemistry and Optical Spectroscopy. In 2005, he received his PhD at the University of Tübingen for his work on a fully automated optical biosensor system where he holds a position as a lecturer for bio-analytics. Dr. Proll has published more than 40 original articles and 6 patents covering his work. He is one of the main inventors of the SCORE technology and was co-founder and CEO of a start-up company whose assets were sold to BioCopy GmbH, for which he worked as Senior Scientist. Since 2020 Dr. Proll holds a position as scientist and assistant lecturer at the University of Tübingen in the field of optical biosensing and joined recently the „Hauptausschuss der Wasserchemischen Gesellschaft“ of the German Association for Chemists (GDCh) and serves as head of the specialist committee for “Sensors”.
Nanotechnology on fibers: New Avenues for Life Science Applications
Andrea Cusano is full Professor of Electronics, Optoelectronics and Photonics at the University of Sannio. His research interests are focused on the suitable merging of optical fibers and nanotechnologies and was the pioneer of the “Lab on fiber Technology” concept, nowadays recognized as an hot topic in nanophotonics. He published over 400 papers on prestigious international journals and communications in well-known international conferences worldwide; he has close to 20 national and international patents currently in charge of prestigious industrial companies. He is co-author of more than 70 invited chapters published in international books, invited papers, key note and plenary lectures in prestigious scientific international journals as well as international conferences. He was a the past Editor in Chief of Journal of Optics and Laser Technology (Elsevier) and the actual Editor in chief for Results in Optics (Elsevier). He was also cofounder of several spin-off companies focused on the development of fiber optic sensing systems for industrial and life science applications: “OptoSmart S.r.l.” in 2005, “MDTech” in 2007, “OptoAdvance” in 2011, Mantid S.r.l. in 2017, Often Medical in 2019, Biotag in 2021. In 2020, he was appointed as Technical Director of the Research Infrastructure (C-NOS: Optoelectronics and Photonics Technologies for Life Science Applications). He holds more than 25 national and international patents, most of them have been transferred to industrial companies.
Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University, USA
Electrochemical, Aptamer-Based Sensors for Continuous Molecular Monitoring in the Body
Netzahualcoyotl (Netz) Arroyo is an Assistant Professor in Pharmacology and Molecular Sciences at Johns Hopkins University School of Medicine. The department was established by John Jacob Abel in 1893 as the first Department of Pharmacology in the United States. Seminal contributions by our department include the discovery of the neurotransmitter epinephrine, the crystallization of insulin, the first measurement of a drug concentration in a human, and the identification of the opiate and insulin receptors. Today, the department is a nexus for collaboration across the school with 10 primary faculty, and an additional 26 secondary faculty conducting research in 14 other departments. Collectively, we focus on a wide range of areas, including drug discovery and design, drug delivery, mass spectrometry (metabolomics, proteomics, and imaging), high-throughput chemistry and screening approaches, cancer mechanisms and therapeutics, drug metabolism/pharmacokinetics, neuropharmacology, glycobiology, lipid biology, and epigenetics. Netz Arroyo received his Ph.D. in Analytical Chemistry from The University of Texas at Austin under electrochemist Allen J. Bard and was a postdoctoral fellow at University of California Santa Barbara under biophysicist Kevin W. Plaxco. As Assistant Professor, he leads a multidisciplinary research group of four graduate students and two postdoctoral fellows focused on the development of biosensing technologies for real-time molecular monitoring in biological systems. More specifically, research in the Arroyo lab aims to expand our understanding therapeutic transport across biological barriers, develop new diagnostic and drug delivery approaches, and expand therapeutic drug monitoring capabilities via wearable devices. These applications are enabled by electrochemical, aptamer-based sensors, a platform co-developed by Dr. Arroyo that allows continuous and real-time molecular measurements within the body.
Department of Chemistry, Federal University of Viçosa, Brazil
Nanoporous Metallic Electrodes for Sensing under Biofouling Conditions
Prof. Tiago received his BSc degree in Chemistry from Federal University of Uberlândia (Brazil) in 2012 with an academic mobility period (2010–2011) at the University of Lisbon (Portugal), MS degree (2015) and PhD degree (2019) in Analytical Chemistry from the Federal University of São Carlos (Brazil). He served as a visiting doctoral researcher (2017) at Virginia Commonwealth University (Richmond, VA, USA). Currently, he is Adjunct Professor of Chemistry at the Federal University of Viçosa, Brazil. His research interests include the development of novel electroanalytical methods, design of nanostructured sensors and biosensors, reuse of agro-industrial residues in nanotechnology and green corrosion inhibitors. He has served as Guest editor of Biosensors and Frontiers in Sensors journals, and as Reviewer of several specialized journals. He has published more than 60 scientific articles yielding an H-factor of 23, two books in the electroanalysis area, 6 book chapters and several papers in congress.
Department of Analytical Chemistry and Environmental Engineering, Faculty of Chemical Engineering and Biotechnologies, University "Politehnica" of Bucharest, Romania
Novel Methods in the Development of Sensing Materials for Electrochemical (Bio)sensors
Stelian Lupu is full professor at the Department of Analytical Chemistry and Environmental Engineering, Faculty of Chemical Engineering and Biotechnology, the University Politehnica of Bucharest. He has earned a Ph.D. degree in 2001 from the University of Bucharest, Romania, and the Habilitation à Diriger des Recherches (HDR Diploma) in 2012 from the University of Besançon, France. He has performed several research stages at the University of Modena, at doctoral and postdoctoral levels, and one postdoctoral research stage at the École Normale Supérieure de Paris. His general research interests include electrochemical sensors and biosensors, microelectrodes and their arrays, and electroanalysis of biologically active compounds and organic/inorganic pollutants. He has coordinated several national grants on electrochemical (bio)sensors based on conducting polymers and composite materials and has developed international and national scientific collaborations with research Groups from Universities of Modena (Italy), Besançon (France), Cadiz (Spain), and Lille (France), the Basque Centre for Materials, Applications & Nanostructures of Leioa (Spain), the Institute of Physical Chemistry of Sofia (Bulgaria), the Institute of Physical Chemistry of Bucharest. He is coordinating Erasmus and Erasmus+ Programs (since 2003 up to the present) with Universities from Modena, Besancon, and Cadiz.
Department of Molecular Medicine, Faculty of Medicine, Universiti Malaya, Malaysia
Nanomaterials-Based Multiplex Aptasensors for the Comprehensive and Rapid Detection of Foodborne Pathogens
Dr. Leo Bey Fen is an assistant professor at the Faculty of Medicine, University of Malaya (UM) and a research fellow at the Nanotechnology and Catalysis Research Centre, UM. She obtained her PhD from the London Centre for Nanotechnology (LCN), Imperial College London (UK). Her research focuses on the development of portable, rapid and sensitive point-of-care devices for pathogen detection. Many of her peer-reviewed papers on topics including nanomaterials synthesis, electrochemistry, biosensors etc. have been published in high-impact journals. Besides, the biosensors developed by her team have received several prestigious awards, including the International Conference and Exposition on Inventions by Institutions of Higher Learning (Pecipta, Gold Award) and Innovation of The Year in Malaysia Medical Device Expo. Dr. Leo also serves as an associate editor for the Electrochemical Environmental Engineering section of Frontiers in Environmental Chemistry and special issues in The Journal of International Medical Research on the topic of ‘Rapid Detection of Global Infectious Disease’. She also serves as a reviewer for scientific papers including nature communications, Scientific Reports (Nature), ACS Applied Nano Materials, ACS Sensors, RSC Advances, Sensors & Diagnostics, Analytical Chemistry, etc.
Department of Chemistry, National and Kapodistrian University of Athens, Greece
3D Printed Electrochemical (Bio)devices
Christos Kokkinos is Associate Professor at the Department of Chemistry, National and Kapodistrian University of Athens, Greece. His research interests include the fabrication of smart sensors and biosensors through microengineering, 3D-printing and other printing technologies. The produced sensors intend to the electrochemical determination of (bio)markers with significance interest in the field of environmental, food and forensic chemistry. Biodevices based on labeling with nanoparticles, as well as wearable enzymatic biosensors are also included in his group working scientific area. Based on his research, more than 60 papers have been published in international peer reviewed journals with high impact factor (mean IF >7).
Department of Electrical and Information Engineering, Politecnico di Bari (Polytechnic University of Bari), Italy
Biosensing by All-Dielectric Metasurfaces
Francesco Dell'Olio obtained his PhD in Information & Communication Technologies in 2010. Since 2022, he has been an Associate Professor of Electronics at the Polytechnic University of Bari, Italy. The research interests of Prof. Dell’Olio are focused on silicon photonics. F. Dell'Olio is co-author of 2 books, published by Springer and World Scientific, more than 50 papers in international peer-reviewed journals and 100 papers published in international conference proceedings. F. Dell'Olio is a member of the editorial board of the international journals Applied Sciences, Biosensors, Chemosensors, and Journal of Sensors, and has served as guest editor for several special issues. Currently, F. Dell'Olio is a reviewer for many international journals in the field of optoelectronics and photonics. F. Dell'Olio is regularly a member of the organizing committee, the program committee, and the local committee of international conferences. F. Dell'Olio has been and is involved in several research projects funded by Italian Ministry of University and Research, the European Space Agency, the Italian Space Agency, and some industrial companies also holding roles with scientific responsibility. Since 2016 F. Dell'Olio has been the scientific director of two research projects funded by the University Research Fund of the Polytechnic University of Bari. F. Dell'Olio has been the beneficiary of funds for its research activities under the Fund for the financing of basic research activities in Italy.
Laboratory for Soft Matter and Biophysics, ZMB, Department of Physics and Astronomy, KU Leuven, Belgium
Spontaneous Detachment Behavior of Eukaryotic Cells in Presence of Temperature Gradients
Patrick Wagner obtained a Ph.D. in Physics in 1994 at TU Darmstadt, Germany. Thereafter, he was a postdoctoral fellow at KU Leuven (Belgium), working on the electrical properties of oxide thin films. In 2001, he became a professor at Hasselt University (Belgium), and switched to the field of biosensors for medical diagnostics. In 2014, he moved back to KU Leuven as a full professor of biophysics and became head of the Laboratory for Soft Matter and Biophysics in 2022. Regarding transducers, his team utilizes impedance analysis, quartz-crystal microbalances, and the heat-transfer method HTM: The latter sensing mechanism relies on the unexpected observation that on-chip denaturation of DNA causes a substantial change of the thermal interface resistance between the chip and the liquid. HTM can be applied to various bioanalytical applications, including the detection of proteins, inflammation markers, bacteria, and cancer cells. At the side of the receptors, the team develops molecularly-imprinted polymers for small-molecule recognition and surface-imprinted polymers for larger targets such as bacteria. Recently, we developed a receptor-free, thermal technique to identify eukaryotic cells and characterize their response to nutrients and toxins. P. Wagner has served as president of the Belgian Physical Society (2006, 2007), as chair of the scientific advisory board of the Kurt-Schwabe-Institute (2016 – 2019), and as a member of the expert panel for interdisciplinary research of the Research Foundation Flanders FWO (ongoing). He was editor-in-chief of the journal Physics-in-Medicine (2016 – 2022), member of the editorial board of SENSORS (since 2018), and serves as guest editor of the annual section “Engineering of Functional Interfaces” in Physica Status Solidi A.
Department of Nuclear Engineering and Materials Science and Engineering, The Pennsylvania State University, University Park, USA
Innovations in Biosensing During Pandemics Through Nano-Enabled Antisense Technology
Prof. Pan is a recognized expert in nanomedicine. He is presently a Dorothy Foehr Huck & J. Lloyd Huck Chair Professor in Nanomedicine and tenured Full Professor in the Pennsylvania State University. His research is highly collaborative and interdisciplinary, centering around the development of novel materials for biomedical applications, immune-nanomedicine, and targeted therapies for stem-like cancer cell with phenotypically screened nanomedicine platforms and biosensing approaches for infectious diseases. Over the years, this research has resulted in >200 high impact peer reviewed publications in scientific journals, many patents, and several technology licensing. He is the founder of four University based early start-ups, including Vitruvian Bio, dedicated to developing HIV-companion diagnostics; InnSight Technologies dedicated for ocular diseases and KaloCyte, Inc, to develop artificial oxygen career for human trauma. In 2016 Dr. Pan received Nanomaterials Letter (NML) Researcher award, in 2017 a Young Innovator Award from Biomedical Engineering Society (BMES), and a Deans Award for Research Excellence in 2018. He is an elected senior member of National Academy of Innovators (NAI), a fellow of Royal Society of Chemistry (FRSC), a Fellow of American Heart Association (FAHA) and an elected fellow of American College of Cardiology (HACC). Professor Pan is an Associate Editor for WIRES Nanomedicine and Nanobiotechnology (Wiley).
Invited Speakers
Aptamers and Aptamer-Based Sensors: New Insights and Novel Applications
George Tsekenis, a biochemist and molecular biologist by training (University of Nottingham, UK), since his PhD studies at Cranfield University, UK has focused on biosensor development due to his keen interest in the interface between the biological world and inorganic materials. As a postdoctoral researcher and currently Head of the Applied Biophysics and Surface Science Laboratory at the Biomedical Research Foundation of the Academy of Athens (BRFAA), he has been involved in more than 15 EU and Nationally-funded projects aimed towards the development of biosensors based on different signal transduction principles as well as biorecognition molecules and had the opportunity to put forward innovative solutions for challenging issues in the field of biochemical assay development and surface functionalization as well as their integration into biosensing platforms and prototyping of novel Lab-on-Chip devices. The main focus of his team's research is gaining a deeper understanding on aptamers through their biophysical characterization and their employment in groundbreaking applications as well as the development of novel, 'universally'-applicable chemistries for surface property tailoring.
Versatile Derivatization of Plasmonic D-shaped Plastic Optical Fiber for Biosensing
I graduated in Physics at the University of Trento in 2000. I worked for many years as a researcher at the Fondazione Bruno Kessler in Trento and at the University of Trento, working on the development of micro- and nanodevices and biosensors for genomics and proteomics. My expertise covers several research fields: development and characterisation of biointerfaces, molecular biology, high-resolution imaging. In the last ten years I was mainly focused on the development of optical biosensors both using aptamers and antibodies as molecular recognition elements. I am the author of more than 60 articles in peer-reviewed scientific journals, co-organiser of three international schools and co-author of three dissertations. Since 2018 I co-founded Indivenire srl, an innovative startup offering an R&D outsourcing service.
Department of Electronic Devices Circuits and Architectures, Politehnica University of Bucharest, Romania
Nano-Structured Metallic Compounds Used as Enzyme Linkers in Integrated Biosensors
Cristian Ravariu received the B.S.(1993), Ph.D (2001), PostDoc (2012) degrees at the Polytechnic University of Bucharest, Romania in the Electronic Devices domain and Bioelectronics. Between '93-'99 he activated as researcher at the Institute of Microtechnology Bucharest, in the field of Electronic Devices simulation-fabrication, Si-technology in clean room. Now, he is Full Professor at Polytechnic University of Bucharest, being interested in novel electronics devices development and integrated biosensors. He has published more than 200 articles in Journals and Proceedings of Conferences. Dr. Ravariu is the current Chairman of Romanian IEEE-Electron Device Chapter. Head of few projects with Bioengineering topics: BioFET transistors for glucose detection, Non-invasive technology for functional characterization of the cellular beta-pancreatic mass, Nano-transistors with thin films implemented through nanotechnologies. Main actual interests: he are searching for Europe collaborators for: double affiliation, for Western Europe specializations stages and/or temporary jobs, Erasmus exhanges collaboration, Marie Curie Grants, European Projects Collaborations in the fields of Nano-Bio-Electronics, Devices Modeling.
Laboratory of Organic Electronics, Department of Life Science, University of Modena and Reggio Emilia, Italy
Electrolyte-Gated Transistors Biosensors for Healthcare and Food Freshness Applications
Matteo Sensi received his master’s degree in Industrial Biotechnologies at the University of Milano-Bicocca(IT) in 2014. He defended his PhD thesis in Chemical Sciences in 2017, in a joint-supervision project between the University of Milano-Bicocca(IT) and the Aix-Marseille University(FR). During the PhD he worked on electrochemical and computational characterization of FeFe-Hydrogenases photochemistry. MS is now research fellow in the Laboratory of Organic Electronics directed by Prof. Fabio Biscarini at the University of Modena and Reggio Emilia, his research since 2018 focuses on development and characterization of electrolyte gated transistors biosensors for healthcare and food industry applications.
Low Cost Electrochemical Sensor for Algal Toxin Detection in Water
Dr Wei Zhang is a currently assistant professor at Department of Chemical Engineering, Swansea University. His main research interest is in developing novel water treatment and monitoring technologies. During his research career, he was the recipient of many prestigious awards, including Australian Endeavour fellowship in 2014, Japan Society for Promotion of Science (JSPS) overseas fellowship in 2015, and Horizon 2020 Marie Skłodowska-Curie Actions (MSCA) fellowship in 2017. He also serves as topic editors for journal Biosensors and Frontiers in Sensors.
Bioelectronic Devices and Therapeutic Applications: The Peripheral Nervous System Stimulation as a Paradigm of the New Bioelectronic Medicine Era
Dimitrios Koutsouras is a Physics Researcher in Implantable Therapeutics at IMEC-NL in Eindhoven (The Netherlands). He received a BS in Physics and a second one in Pharmacy from Aristotle University of Thessaloniki (Greece), and a MSc in Materials Physics from the same university. He then obtained a PhD in Organic Bioelectronics from École des Mines de Saint-Etienne in Gardanne (France), before moving to Mainz (Germany) to work as a postdoctoral researcher at the Max Planck Institute for Polymer Research (MPIP). At MPIP he worked on conducting polymer devices for biosensing, biomedical and pharmaceutical applications. His research is focused on bioelectronic devices for improved biomedical solutions. In particular, he is interested in the designing, (micro)fabrication and clinical translation of multimodal bioelectronic devices endowed with biosensing, stimulating and therapeutic functionalities.
College of Science and General Studies, Alfaisal University, Saudi Arabia
Microfabrication of Versatile Microfluidic Devices for In Vitro Microphysiological Systems
Qasem Ramadan received his PhD from Nanyang Technological University in 2004; afterwards, he joined the A-STAR’s institute of microelectronics in Singapore as a senior research engineer. In October 2008, he joined the Swiss Federal Institute of Technology in Lausanne (EPFL) where he worked on developing miniaturized in vitro models of the human gastrointestinal tract for nutrition analysis. In June 2013 he rejoined the A*STAR Institute of Microelectronics as a senior research scientist focusing on developing organ-on-a-chip platforms for drug screening and disease modelling. Since 2019, he is with Alfaisal University. His current research interest span is developing in vitro immune active microphsiological systems for disease modelling.
Department of Chemistry, University of Gothenburg, Sweden and Institute for advanced studies in basic sciences. Iran.
Advances in (Bio)sensors for Single Intracellular Vesicles Analysis, a Key Organelle in Cellular Communication
Amir Hatami, Research associate at department of chemistry and molecular biology university of Gothenburg, Gothenburg-Sweden. He graduated in analytical chemistry in 2014 from University of Shahid Chamran, Iran-2014. Then, He joined the Nanotechnology Group-Sharif University-Iran, after that, he has joined Prof. Andrew Ewing and Prof. P. Rorsman groups -Gothenburg University where he has been awarded the Wallenburg Fellowship-Sweden, Mari-curie fellowship grant-EU, and Sahlgrenska academy Grant-Sweden etc. He also currently works actively with Macmaster, IASBS and Barcelona universities. The research interests are in Bioanalytical chemistry, Nano-micro-macro-scales (bio)sensors. He is author of 33 scientific publications and 6 review papers, h-index=22, 4 invited speakers, 2 book-chapters, co-organizer of 2 scientific meetings, journal, member of international scientific societies (Swedish Chemical Society, International Electrochemical Society (ISE), Iranian Society of Chemistry). He has acted as a reviewer in more than 10 different international journals. He is Guest Associate Editor of Frontiers in Bioengineering and Biotechnology-in Biosensors section and has also served as Guest Editor of several Special Issues for Biosensors journal.
List of accepted submissions (51)
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sciforum-071070 | Glyphosate detection in urine with paper origami biosensors: a sustainable strategy to answer analytical challenges |
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Francesco Fama ,
Noemi Colozza ,
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Chiara Zanardi
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The use of pesticides has been continuously increasing worldwide since their introduction in the global market, with the aim of fulfilling the needs of the growing population. While their monitoring in the environment has been thoroughly addressed, the bioaccumulation of pesticides in the human body is an ongoing challenge, due to the complexity of the biological matrices in which pesticides tend to accumulate (e.g., urine, blood, sweat, and more). Most of the developed strategies rely on time-consuming sample preparation or expensive and polluting reagents for the construction of the sensing platform. In the view of developing a green alternative device to handle pesticide analysis in biofluids, we designed an enzymatic paper-based electrochemical sensor for glyphosate (GLY) detection in human urine. The pesticide quantification is obtained by measuring the grade of enzyme inhibition by both GLY and uric acid (UA), the latter being one of the principal components of human urine. GLY detection is carried out by measuring the initial and residual enzymatic activity in chronoamperometric tests, taking into consideration the contribution of UA to the inhibition. In addition to the specific application here described, this work aims at providing an emblematic example of how to design green sensing solutions for addressing analytical challenges related to health control, delivering low-impact methods based on sustainable materials (e.g., paper), non-toxic reagents, and minimal waste production while ensuring competitive analytical performances. |
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sciforum-071192 | Enhanced Electroanalysis of Lead and Cadmium in Multi-Matrices with Paper-based Strips |
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Michele Spinelli ,
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Heavy metals ions (HMI) are micropollutants that represent a growing environmental problem, as they have influenced various components of the environment, such as terrestrial and aquatic biota. Among HMI, lead and cadmium are highly toxic, and even small doses can lead to harmful effects on human health. Thus, rapid methods to detect these metals in multi-matrices are urgently required. Here, an electrochemical sensor screen-printed onto a flexible substrate has been coupled with a paper-based platform for the determination of HMI in clinical, environmental and food matrices have been developed. The bismuth film-based flexible device has been optimized and it has been able to detect cadmium and lead, respectively, down to the detection limit of 1.3 and 2 ppb. The use of chromatographic paper has allowed to improve the sensitivity towards the detection of HMI, because of the porosity that allowed to pre-concentrate species. The combination of this platform with a paper-based one has allowed to enhance the sensitivity of the whole device, with a detection limit of 0.3 and 0.5 ppb, respectively, to cadmium and lead, and offers the possibility to tune the sensitivity according to needs, e.g., improving the number of pre-concentration steps. The electrochemical sensor was evaluated in drinking water, mussel and blood serum, demonstrating how these hybrid polyester-paper electrochemical strips can significantly lower the time and costs for on-site measurements, through analytical methods of simple use. The accuracy has been evaluated by comparison with ICP-MS measurements, giving satisfactory results. DOI 10.1149/1945-7111/ac5c98 |
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sciforum-071035 | 3D printed electrochemical (bio)devices | N/A |
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Three-dimensional (3D) printing has gained significant attention from industry and research laboratories, as it empowers the end user with the freedom to create in-house and on-demand specialized electrochemical systems adapted to immediate bioanalytical needs. Fused deposition modeling (FDM) is based on the CAD design of the sensor and its printing from thermoplastic filaments. FDM presents advantageous features such as low-cost portable printers, ease of operation, flexibility in the design, design transferability, and thus, it can complement and in some cases replace, existing fabrication technologies [1,2,3]. This presentation will discuss our recent developments of 3D-printed integrated chips and their applications to electrochemical biosensing [4,5,6]. The devices are printed from specific filaments (conductive and non-conductive) at different sizes and shapes, by a dual extruder 3D printer, in order to fit to the demands of various applications. More specifically, integrated all-3D-printed electrochemical microtitration wells (e-wells) for the in-situ and micro-volume quantum dot based bioassays will be described. Besides, a 3D printed 4-electrode biochip for the enzymatic simultaneous determination of two biomarkers and a 3D printed wearable glucose monitoring device in the form of an electrochemical ring (e-ring) will be presented.
References
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sciforum-071365 | A smartphone-addressable aptamer-based lateral flow biosensor for ochratoxin A |
Electra Mermiga ,
Varvara Pagkali ,
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Ochratoxin A (OTA) is a mycotoxin produced by several fungal species and various studies have shown that OTA can cause several adverse health effects to animals and humans through its consumption in contaminated plant foods such as coffee, beer, wine, corn, wheat, oats and vegetables [1]. OTA has been shown to be nephrotoxic, teratogenic, immunotoxic, and carcinogenic in human health. In particular, the International Agency for Research on Cancer has classified OTA as a group 2B carcinogen [2]. Due to the toxicity of OTA , the European Union has set maximum limits (MLs) for OTA in foods in the range of 0.5–10 μg kg−1 [2]. Therefore, the development of a cheap, sensitive and rapid method for OTA detection in plant-based foods is essential. The detection of OTA in food is mostly based on chromatographic techniques, which although powerful , require expensive equipment, trained personel and complex sample preparation [1,2]. Enzyme-linked immunosorbent assay s(ELISA) and immunochromatographic assays are portable, convenient and simple but require expensive and unstable antibodies and normally [3,4]. On the contrary aptamer-based biosensors employ relative inexpensive and stable single stranded oligonucleotides as biorecognition elements, which makes them ideal for rapid on-site detection of OTA [2,5], especially when combined with smartphone-based detection [6]. In this work, we describe a simple, portable and cost-efficient lateral flow biosensor for OTA. The biosensor utilizes an OTA-specific aptamer for biorecognition and is based on a lateral flow assay using a device consisting of a sample pad, a conjugate pad, a test and a control zone, as well as an absorbent pad. The conjugate PAD is loaded with OTA aptamer-AuNPs congugates while the test and control zones are loaded with a specific and a universal probe, respectively. The principle of the assay is that the OTA present in the sample combines with the OTA aptamer-AuNPs congugates and prevents the interaction between the specific probe in the test line and the OTA aptamer-AuNPs congugates; therefore, the intensity of the test line decreases as the concentration of OTA in the sample increases. Quantification of OTA is performed by reflectance calorimetry using a smartphone and image analysis. All the parameters of the assay were investigated in detail and the analytical features were established. References [1] Atumo S (2020) A Review of Ochratoxin A Occurrence, Condition for the Formation and Analytical Methods. Int J Agric Sc Food Technol 6(2): 180-185. DOI: 10.17352/2455-815X.000071 [2] Chen, X., Gao, D., Sun, F. et al. Nanomaterial-based aptamer biosensors for ochratoxin A detection: a review. Anal Bioanal Chem 414, 2953–2969 (2022). https://doi.org/10.1007/s00216-022-03960-5 [3] Meulenberg EP. Immunochemical methods for ochratoxin A detection: a review. Toxins (Basel). 2012 Apr;4(4):244-66. doi: 10.3390/toxins4040244. Epub 2012 Apr 13. PMID: 22606375; PMCID: PMC3347002 [4] Bazin I, Nabais E, Lopez-Ferber M. Rapid visual tests: fast and reliable detection of ochratoxin A. Toxins. 2010 Sep;2(9):2230-2241. DOI: 10.3390/toxins2092230 [5] Ha, T.H. Recent Advances for the Detection of Ochratoxin A. Toxins 2015, 7, 5276-5300. https://doi.org/10.3390/toxins7124882 [6] Madrid RE, Ashur Ramallo F, Barraza DE, Chaile RE. Smartphone-Based Biosensor Devices for Healthcare: Technologies, Trends, and Adoption by End-Users. Bioengineering (Basel). 2022 Mar 1;9(3):101. doi: 10.3390/bioengineering9030101 |
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sciforum-071315 | Elaboration and characterization of enzymatic biosensor for quaternary ammonium compounds | , , | N/A |
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Biocidal disinfectants are used daily throughout the food chain to limit the development of undesirable microorganisms present in the environment or on surfaces in contact with foodstuffs or animal feed. The presence of residues of these biocidal products is an issue for human health especially if they are not completely removed during rinsing operations. Today, we aim to develop innovative electrochemical biosensors as powerful analytical methods to detect these residues of biocides. Enzyme-based biosensors are known to be more sensitive and selective. So far, only one conductometric sensor is known at present for the detection of surfactants [1]. In this light, we suggested applying the acetylcholinesterase-based voltammetric biosensor for inhibitory analysis of quaternary ammonium compounds (QACs). In this work, we elaborated an enzymatic sensor based on bionanomaterials film consisting of a fil of carboxylic acid functionalized multi-walled carbon nanotubes (c-MWCNT) modified with the acetylcholinesterase enzyme. In addition to their mechanical stability and good electric conductivity, the c-MWCNT in particular display a large number of binding sites available for enzyme immobilization. These cholinesterase-based sensors are very sensitive and allow for reaching low limits of detection. Cyclic voltammetry was used to characterize the sensing film deposited onto the surface of electrodes such as glassy carbon and gold electrodes (Au250AT, Au250BT). The acetylcholinesterase sensors that exhibited good repeatability and stability were applied to the detection of residues of QACs in milk samples. [1] DOI 10.1088/0957-0233/23/6/065801 |
Live Session Program
IECB 2023 | Live Session I
Session Chair: Professor Benoît PIRO
Date: 8 May 2023
Time: 15:00(CEST) | 09:00(EDT) | 21:00(CST Asia)
Time in CEST | Speaker | Title |
15:00-15:05 | Opening speech and the introduction from the chair | |
15:05-15:30 | Professor Sergey A. Piletsky University of Leicester |
MIP Nanoparticles for Diagnostics and Imaging Applications |
15:30-15:50 | Dr. Stefano Cinti University of Naples “Federico II” |
Advancing Electroanalysis with the Use of Paper-Based Substrates |
15:50-16:10 | Professor María Jesús Lobo-Castañón University of Oviedo |
Electrochemical Detection of Circulating lncRNA for Cancer Diagnosis |
16:10-16:30 | Prof. Dr. Stelian Lupu University "Politehnica" of Bucharest |
Novel Methods in the Development of Sensing Materials for Electrochemical (Bio)sensors |
16:30-16:40 | Break | |
16:40-17:00 | Prof. Dr. Christos Kokkinos National and Kapodistrian University of Athens |
3D Printed Electrochemical (Bio)devices |
17:00-17:20 | Dr. Günther Proll University of Tübingen |
The Future of Reflectometric Biosensing |
17:20-17:30 | Discussion and Q&A |
IECB 2023 | Live Session II
Session Chair: Professor Cecilia Cristea
Date: 9 May 2023
Time: 15:00(CEST) | 09:00(EDT) | 21:00(CST Asia)
Time in CEST | Speaker | Title |
15:00-15:05 | Professor Cecilia Cristea University of Medicine and Pharmacy 4 |
Introduction from the session chair |
15:05-15:25 | Professor Andrea Cusano University of Sannio |
Nanotechnology on fibers: New Avenues for Life Science Applications |
15:25-15:45 | Dr. Netz Arroyo Johns Hopkins University |
Electrochemical, Aptamer-Based Sensors for Continuous Molecular Monitoring in the Body |
15:45-16:05 | Dr. George Tsekenis Biomedical Research Foundation of the Academy of Athens |
Aptamers and Aptamer-Based Sensors: |
16:05-16:25 | Dr. Dimitrios Koutsouras IMEC-NL in Eindhoven |
Bioelectronic Devices and Therapeutic Applications: The Peripheral Nervous System Stimulation as a Paradigm of the New Bioelectronic Medicine Era |
16:25-16:30 | Discussion and Q&A |
IECB 2023 | Live Session III
Session Chair: Professor Eden Morales-Narváez
Date: 16 May 2023
Time: 15:00(CEST) | 09:00(EDT) | 21:00(CST Asia)
Time in CEST | Speaker | Title |
15:00-15:05 | Professor Eden Morales-Narváez Center for Applied Physics and Advanced Technology of the National Autonomous University of Mexico (UNAM) |
Introduction from the session chair |
15:05-15:25 | Dr. Leo Bey Fen Universiti Malaya |
Nanomaterials-Based Multiplex Aptasensors for the Comprehensive and Rapid Detection of Foodborne Pathogens |
15:25-15:45 | Professor Patrick Wagner KU Leuven |
Spontaneous Detachment Behavior of Eukaryotic Cells in Presence of Temperature Gradients |
15:45-16:05 | Professor Cristian Ravariu Politehnica University of Bucharest |
Nano-Structured Metallic Compounds Used as Enzyme Linkers in Integrated Biosensors |
16:05-16:15 | Break | |
16:15-16:35 | Dr. Matteo Sensi University of Modena and Reggio Emilia |
Electrolyte-Gated Transistors Biosensors for Healthcare and Food Freshness Applications |
16:35-16:55 | Prof. Dr. Tiago Almeida Silva Federal University of Viçosa |
Nanoporous Metallic Electrodes for Sensing under Biofouling Conditions |
16:55-17:00 | Discussion and Q&A |
IECB 2023 | Live Session IV
Session Chair: Professor Michael Thompson
Date: 18 May 2023
Time: 15:00(CEST) | 09:00(EDT) | 21:00(CST Asia)
Time in CEST | Speaker | Title |
15:00-15:05 | Professor Michael Thompson University of Toronto |
Introduction from the session chair |
15:05-15:25 | Dr. Francesco Dell'olio Polytechnic University of Bari |
Biosensing by All-Dielectric Metasurfaces |
15:25-15:45 | Dr. Qasem Ramadan Alfaisal University |
Integration of Sensing Elements into Microphysiological Systems |
15:45-16:05 | Dr. Amir Hatamie University of Gothenburg |
Advances in (Bio)sensors for Single Intracellular Vesicles Analysis, a Key Organelle in Cellular Communication |
16:05-16:15 | Break | |
16:15-16:35 | Dr. Laura Pasquardini Indivenire srl |
Versatile Derivatization of Plasmonic D-shaped Plastic Optical Fiber for Biosensing |
16:35-16:55 | Dr. Wei Zhang Swansea University |
Low Cost Electrochemical Sensor for Algal Toxin Detection in Water |
16:55-17:15 |
Professor Dipanjan Pan |
Innovations in Biosensing During Pandemics Through Nano-Enabled Antisense Technology |
17:15-17:20 | Discussion and Q&A |
Live Session Recordings
Sessions
B. Ingestible, Implantable and Wearable Biosensors
C. Smartphone-based Biosensors
D. The Evolution of Biological Recognition Elements in Biosensors
E. Microfabrication and Printing Techniques in Biosensors
F. Nanomaterials and Smart Surfaces in Biosensors
G. Technological Advancements in Biosensor Actuators
H. Paper-based Biosensors
I. Optical and Photonic Biosensors
Event Awards
To acknowledge the support of the conference's esteemed authors and recognize their outstanding scientific accomplishments, Biosensors would like to give awards for the best paper and best poster as elected by the members of the scientific committee. We look forward to posting your contributions.
The Awards
Number of Awards Available: 1
Best Paper Award Winner
Title: In Silico Evaluation of Folding and Structural Stability of Aptamers for Application in the Design of a Biosensor for Testosterone Detection
Author: Ariadna Medina, Aurora Antonio, Ana Laura Torres
Number of Awards Available: 3
1. Title: Hydrogel-coated nanonet-based field-effect transistors for SARS-CoV-2 spike protein detection in high ionic strength samples
Authors: Alexandra Parichenko, Wonyeong Choi, Seonghwan Shin, Marlena Stadtmüller, Akbar Teuku Fawzul, Carsten Werner, Jeong-Soo Lee, Bergoi Ibarlucea, Gianaurelio Cuniberti
2. Title: Features of the interaction of biomolecules with rigid carbon networks: QCM study of the adsorption of gaseous analytes on a C60 surface coated with ovalbumin
Authors: Ivanna Kruglenko, Sergii Kravchenko, Julia Burlachenko, Petro Kruglenko, Borys Snopok
3. Title: Engineering next generation bioluminescent Ca2+ sensors through directed evolution
Authors: Yufeng Zhao, Sungmoo Lee, Robert Campbell, Michael Lin
Number of Awards Available: 1
Best Presentation Award Winner
Title: 3D printed electrochemical (bio)devices
Author: Christos Kokkinos
Terms and Conditions:
Criteria for Evaluation of Best Paper Award:
Full paper must be submitted to IECB 2023;
Originality/novelty of the paper;
Significance of content;
Scientific soundness;
Interest to the readers;
English language and style.
Requirements for Best Poster Award:
Posters should have the following information.
Title (with authors and affiliations);
Introduction/Objectives/Aims;
Methods;
Results;
Conclusion;
References;
Acknowledgements;
Contact information;
A 3-minute video presentation;
Award Supporter
LinkZill was founded in Jan. 2019 in Wuhan and relocated its headquarters to Hangzhou in Jan. 2020, then started the R&D center in Shanghai in 2021. LinkZill's core value is "leading the technology–领, be dedicated and honest from the beginning to the end–挚". LinkZill is devoted to making technology serve people better and more efficiently. LinkZill's core products are thin-film transistor (TFT) semiconductor chips (including corresponding functional materials and portable test/drive systems), with the applications of high-throughput DNA synthesis, active-matrix digital microfluidics, high-throughput biochemical/photoelectric sensor, and cutting-edge scientific research. |
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PalmSens BV was founded in 2001 by Dr. Kees van Velzen, one of the driving forces in the field of potentiostat digitization in the late ’80s and ’90s. PalmSens BV was the first company to reduce a research-grade potentiostat to a size that fits in your pocket. At PalmSens we are committed to making electrochemistry easier, more portable, and more accessible for novice and advanced researchers and entrepreneurs. We provide a comprehensive range of instruments for most types of electrochemistry with an emphasis on mobility. We manufacture the world’s smallest commercially available potentiostat module with EIS capabilities: the EmStat Pico. While our unique flagship instrument, the PalmSens4, is one of the most versatile and compact frequency response analysis (FRA) / EIS capable device in the market. For more detail: https://www.palmsens.com/ |
Conference Secretariat
Ms. Ellie Liu
Ms. Russell Wang
Email: iecb2023@mdpi.com
A. Artificial Intelligence in Biosensors
Session Chair
Dr. Jun Chen, Department of Bioengineering, University of California, USA
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B. Ingestible, Implantable and Wearable Biosensors
Session Chair
Professor Huanyu Cheng, Department of Engineering Science and Mechanics, The Pennsylvania State University, USA
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C. Smartphone-based Biosensors
Session Chair
Dr. Oleh Smutok, Department of Chemistry & Biomolecular Science, Clarkson University, Potsdam, NY, USA
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D. The Evolution of Biological Recognition Elements in Biosensors
Session Chairs
Professor Xiangheng Niu, School of Public Health, Hengyang Medical School, University of South China, China
Dr. Michael G. Weller, Division 1.5 Protein Analysis, Federal Institute for Materials Research and Testing (BAM), Germany
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E. Microfabrication and Printing Techniques in Biosensors
Session Chair
Professor Cecilia Cristea, Analytical Chemistry Department, Faculty of Pharmacy, "Iuliu Haţieganu" University of Medicine and Pharmacy 4, Romania
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F. Nanomaterials and Smart Surfaces in Biosensors
Session Chairs
Professor Evgeny Katz, Department of Chemistry & Biomolecular Science, Clarkson University, USA
Professor Danila Moscone, Department of Chemical Sciences and Technologies, Università degli Studi di Roma Tor Vergata, Italy
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G. Technological Advancements in Biosensor Actuators
Session Chair
Professor Benoît PIRO, Chemistry Department, University Paris Diderot, France
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H. Paper-based Biosensors
Session Chair
Professor Eden Morales-Narváez, Biophotonic Nanosensors Laboratory, Centro de Investigaciones en Óptica A.C., León 37150, Mexico
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I. Optical and Photonic Biosensors
Session Chairs
Dr. Shaopeng Wang, School of Biological and Health Systems Engineering and Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA
Professor Chenzhong Li, Center for Cellular and Molecular Diagnostics , School of Medicine, Tulane University, USA
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