Biofabrication Frontiers

Edited by: Dr. Mohsen Akbari

The ‘Biofabrication and Tissue Engineering’ section of Micromachines focuses on cutting-edge research and innovation in the design, fabrication, and application of biologically functional constructs for regenerative medicine, disease modeling, and drug discovery, with a strong emphasis on bioprinting technologies, including the development of advanced bioinks, 3D/4D printing techniques, and scaffold-free approaches to the creation of complex, multicellular tissues. It also explores organs on chips, leveraging microfabrication to create physiologically relevant models for studying organ-level functions, disease mechanisms, and drug responses, bridging the gap between traditional models and clinical applications. This section highlights the role of biomaterials, such as smart hydrogels, nanocomposites, and decellularized matrices, in directing cellular behavior, promoting tissue regeneration, and enabling the integration of engineered constructs with host tissues. Additionally, it addresses the critical aspects of commercialization and translation, focusing on scaling up technologies, navigating regulatory pathways, and fostering market adoption to accelerate the transition of biofabrication innovations from the lab to clinical and industrial applications, ultimately advancing human health.

This section welcomes original research articles, reviews, perspectives, and technical notes that contribute to the advancement of biofabrication and tissue engineering, promoting interdisciplinary collaboration and driving the field toward transformative solutions for global healthcare challenges.