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Synthesis of α-acyloxycarboxamides via Passerini reaction.
Published:
14 November 2021
by MDPI
in The 25th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
https://doi.org/10.3390/ecsoc-25-11733
(registering DOI)
Abstract:
The one-pot synthesis of α-acyloxycarboxamides is described. The products were obtained in 63 to 80% overall yields via a facile, efficient, and environmentally friendly strategy under catalyst-free conditions. We study the effect of the carboxylic acid component in the scope of the strategy
Keywords: Passerini reaction (P-3CR); α-acyloxycarboxamides; Ultrasound irradiation