Release of catecholamines from pyrenylmethyl urethane conjugates by light

Susana Costa; M. Sameiro Gonçalves; Maria José Fernandes

doi:10.3390/ecsoc-13-00163

Previous Article in event

Synthesis of some 5,9,14,18,23,27,32,36-octabutoxynaphthalocyanine metal complexes in modified microwave oven

Previous Article in session

4-(Hydroxymethyl)-6-methoxy-2-oxo-2H-benzo[h]benzopyran-ß-alanine conjugate: synthesis and photocleavage

Next Article in event

Efficient Catalytic Synthesis of primary Carbamates using Preyssler heteropolyacid catalyst, H14[NaP5W30O110] under solvent-free and in Green conditions

Release of catecholamines from pyrenylmethyl urethane conjugates by light

Susana P. G. Costa

^*,

M. Sameiro T. Gonçalves

Maria José G. Fernandes

¹ Centro de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal

Published: 31 October 2009 by MDPI in The 13th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-13-00163

Abstract: A fluorescent pyrenylmethyl moiety was coupled to the N-terminus of a series of catecholamines. The behaviour of the corresponding fluorescent conjugates towards photocleavage was evaluated by irradiation in MeOH/HEPES buffer (80:20) solution, in a photochemical reactor at different wavelengths (254, 300, 350 and 419 nm), followed by HPLC/UV monitoring.

Keywords: Pyrene; Catecholamines; Photocleavable protecting groups

View paper View Poster

49 Reads
0 Recommendations

Susana Costa

M. Sameiro Gonçalves

Maria José Fernandes