Steroidal Pyrazines, synthetic Advances and biological Activity

E. Winterfeldt

doi:10.3390/ecsoc-2-01692

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A Chemical Synthesis of Porphobilinogen Imitating the Pathway Proposed by Shemin for the Biosynthesis: Comparing Inhibition Studies with Investigations of Chemical Reactivity

Steroidal Pyrazines, synthetic Advances and biological Activity

E. Winterfeldt

¹ Institut für organische Chemie der Universität Hannover, Schneiderberg 1b, D-30167 Hannover

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session Medicinal and Bioorganic Application of Organic Synthesis

https://doi.org/10.3390/ecsoc-2-01692

Abstract: After the novel and unusual structure of the cephalostatins (scheme 1) had been elucidated 1 and the limited availability of these powerful cytotoxins had been realized2, synthetic efforts aiming at compounds of this type became known from various places in the world.

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E. Winterfeldt