Predicting the Probable Receptor Targets for a Potential Drugs
Based on the Assessment of Their Similarity With Endogenous Ligands

Yulia Borodina; Dimitrii Filimonov; Vladimir Poroikov

doi:10.3390/ecsoc-2-01705

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Predicting the Probable Receptor Targets for a Potential Drugs Based on the Assessment of Their Similarity With Endogenous Ligands

Yulia Borodina

^*,

Dimitrii Filimonov

Vladimir Poroikov

¹ Institute of Biomedical Chemistry RAMS, Pogodinskaya Street, 10, Moscow, 119832, Russia

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session Information and Compound Archives Management and Internet Application

https://doi.org/10.3390/ecsoc-2-01705

Abstract: Todays pharmacology supposes that pharmaceutical agents interact with various physiological receptors which are the targets for neurotransmitters, hormones and other endogenous bioregulators [1]. The same physiological effects can be induced by activation/inhibition of different receptors. Contrary, interaction with several receptors can decrease the effects, induced by each receptor separately. Therefore, the prediction of probable receptor targets for substance is important for design of agent with desirable pharmacological effect.

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Yulia Borodina

Dimitrii Filimonov

Vladimir Poroikov