The T1 Linker: Multidirectional Cleavage for Solid Phase Organic Synthesis.

Stefan Bräse; Stefan Dahmen; Matthias Lormann

doi:10.3390/ecsoc-3-01724

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A New Tungsten Complex Derived from [(Diphenylphosphino)methyl]diphenylphosphine oxide.

The T1 Linker: Multidirectional Cleavage for Solid Phase Organic Synthesis.

Stefan Bräse

^*,

Stefan Dahmen

Matthias Lormann

¹ RWTH Aachen, Institut für Organische Chemie, Professor-Pirlet-Str. 1, D-52074 Aachen, Germany

Published: 01 November 1999 by MDPI in The 3rd International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-3-01724

Abstract: The T1 linker for the attachment of arenes has been described. Various transformations yielded modified arenes. The cleavage from the resin has been conducted to give hydrocarbons ("Traceless linker"), heterocycles (Richter reaction), arylated, alkenylated and alkylated arenes (Heck cleavage protocol), haloarenes, phenols, biaryls and azo compounds. This method is applicable to parallel synthesis and automation.

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Stefan Bräse

Stefan Dahmen

Matthias Lormann