Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues

Jozef Gonda; Miroslava Martinková; Kvetoslava Pomikalová

doi:10.3390/ecsoc-13-00179

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Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues

Jozef Gonda

Miroslava Martinková

Kvetoslava Pomikalová

¹ Institute of Chemical Sciences, Department of Organic Chemistry, P. J. Šafárik University, Moyzesova 11, Košice, Slovak Republic

Published: 31 October 2009 by MDPI in The 13th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-13-00179

Abstract: An efficient strereocontrolled synthesis of substituted oxazolidin-2-one synthon 11 as the key intermediate in the synthesis of FTY720 analogues starting from the highly functionalized furanose scaffold 21 is reported.

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Jozef Gonda

Miroslava Martinková

Kvetoslava Pomikalová