A Straightforward Route to Enantiopure Pyrrolizidines by Cycloaddition to Pyrroline N-Oxides Derived from the Chiral Pool

Valentina Fedi; Alberto Brandi; Andrea Goti

doi:10.3390/ecsoc-1-02011

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A Straightforward Route to Enantiopure Pyrrolizidines by Cycloaddition to Pyrroline N-Oxides Derived from the Chiral Pool

Valentina Fedi

Alberto Brandi

Andrea Goti

¹ Centro di Studio C.N.R. sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni (CSCEA), Dipartimento di Chimica organica "Ugo Schiff", Universita di Firenze, via G. Capponi 9, I-50121 Firenze, Italy.

Published: 01 September 1997 by MDPI in The 1st International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-1-02011

Abstract: We have recently reported the synthesis of enantiopure 3-heterosubstituted pyrroline N-oxides of type 1 and 2 (Scheme 1) obtained by oxidation of the corresponding hydroxylamines, in turn available in large amounts from L-malic and L-aspartic acids, respectively.1

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Valentina Fedi

Alberto Brandi

Andrea Goti