Resin-bound Isothiocyanates and their Synthetic Equivalents as Intermediates for the Solid-Phase Synthesis of Substituted Thiophenes

Henrik Stephensen; Florencio Doerwald

doi:10.3390/ecsoc-1-02055

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Resin-bound Isothiocyanates and their Synthetic Equivalents as Intermediates for the Solid-Phase Synthesis of Substituted Thiophenes

Henrik Stephensen

Florencio Zaragoza Doerwald

¹ Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Maaloev, Denmark

Published: 01 September 1997 by MDPI in The 1st International Electronic Conference on Synthetic Organic Chemistry session Combinatorial Synthesis and Automation

https://doi.org/10.3390/ecsoc-1-02055

Abstract: Highly reactive, polystyrene-bound thiocarbamoyl chlorides and isothiocyanates have been used as key intermediates in a new, robust solid-phase synthesis of substituted thiophenes.

Keywords: solid-phase synthesis, thiophenes, combinatorial chemistry.

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Henrik Stephensen

Florencio Doerwald