Due to its significant environmental impact, the built environment faces growing pressure to transition toward more sustainable practices. Biomimicry, a novel field of practice that entails design and innovation inspired by nature’s time-tested strategies, offers a promising pathway to enhance sustainability in construction. Hence, this study explores the perceived benefits of applying biomimicry principles within the construction sector, aiming to identify the key dimensions underpinning its transformative potential. An exploratory factor analysis (EFA) was conducted based on data collected through a structured questionnaire survey administered to 120 purposively sampled, duly registered, practising construction and biomimicry professionals in South Africa. The instrument captured perceptions of environmental, economic, and socio-functional benefits of biomimicry adoption and implementation. The EFA revealed four principal factors: socio-economic and health benefits, ecological resilience, performance enhancement and green market efficiency. These four factors cumulatively accounted for approximately 70% of the total variance, indicating a strong internal structure of the perceived benefits. The findings demonstrate that stakeholders perceive biomimicry as a tool for reducing environmental footprints and as a catalyst for innovation, circularity, and regenerative design practices in the built environment. This research contributes to the emerging discourse on biomimicry in the built environment by providing empirical evidence on its multifaceted value. It highlights the importance of integrating natural design intelligence into construction to foster more adaptive, efficient, resilient and sustainable systems. This paper recommends policy support, interdisciplinary collaboration, and further research to operationalise biomimicry within mainstream construction processes.