Rice cultivation in the Saharanpur region of Western Uttar Pradesh, particularly for the paddy crop PB 112 during the 2022 season, is crucial for local food security but faces significant challenges in sustainable water and pesticide management. Traditional methods of irrigation and pest control are not only inefficient but also contribute to substantial environmental degradation through excessive water consumption and contamination from pesticide runoff. This study aims to address these challenges by investigating the application of advanced UAV-based spraying technologies, emphasizing the role of nozzle design in enhancing agricultural practices. A series of comprehensive field experiments were conducted to compare various UAV nozzle types, each engineered for optimized spray patterns and droplet sizes suitable for the unique topographical and canopy density variations in the region. These experiments utilized cutting-edge technology, including water flow meters and spectral sensors mounted on drones, to precisely measure the efficacy of each nozzle type in terms of water conservation and accurate pesticide distribution. Preliminary results from the trials indicate that specific nozzle types, particularly those capable of producing ultra-fine droplets, significantly reduce water and pesticide usage—by up to 40% compared to conventional spraying methods. The adoption of these specialized nozzles not only enhanced the targeted coverage area and improved absorption rates by the crops but also substantially minimized the environmental impact. This was evidenced by marked reductions in both runoff and evaporation losses, showcasing the potential of UAV technology to transform agricultural practices. The findings from this research highlight the critical importance of nozzle technology in optimizing UAV spraying applications, demonstrating its viability as a scalable solution for sustainable agriculture in regions suffering from water scarcity and environmental challenges like Saharanpur. This study contributes valuable insights into the design and implementation of precision agriculture tools that can lead to more sustainable cultivation practices and better resource management in agrarian communities.