Sericulture is an agro-based industry that supports rural development, environmental sustainability, and socio-economic upliftment. Recognized for its eco-friendly nature and inclusivity, sericulture provides livelihood opportunities, particularly for marginalized rural communities. The Don Mariano Marcos Memorial State University–Sericulture Research and Development Institute (DMMMSU-SRDI) in the Philippines implemented extension projects in Binalonan, Pangasinan, from 2018 to 2023, supported by the Senator Loren Legarda Fund and DMMMSU-SRDI Regular Fund. These projects aimed to demonstrate sustainable sericulture practices, assess profitability, and promote employment and environmental benefits through pilot farms. The initiative involved sapling and mulberry leaf production, silkworm rearing, and the utilization of sericulture by-products. Best practices included sapling propagation (pot and plot methods), rainfed mulberry establishment (0.9 ha), rearing house construction, synchronized silkworm rearing, and value-adding activities. Over five years, 69 silkworm batches were reared using 52.05 boxes of fourth-instar larvae, fed with over 144,000 kg of mulberry leaves. This resulted in 1,377.19 kg of fresh cocoons, generating PHP 411,320.00 in sales and a net income of PHP 248,164.10 with a return on investment (ROI) of 155.17%. Furthermore, additional income was generated through sericulture by-products (PHP 27,307.00; ROI: 94.93%). Overall, farmer income increased by 131.38%, and the projects created 306.46 person-days of employment valued at PHP 75,372.50. These findings underscore the viability of sericulture as a low-capital, high-return rural enterprise, contributing to agricultural diversification, environmental restoration, and rural socio-economic resilience.