Noncommunicable diseases are the cause of many deaths around the world. Heart disease is the leading cause of death, as well as kidney disease caused by diabetes. These illnesses depend on their sufferers' dietary patterns, which are usually characterised by high sugar consumption. Consequently, some alternatives, such as nonnutritive sweeteners, have been developed. This food additive has no caloric input and mimics the sweet taste of food, helping consumers to reduce their sugar consumption or avoid consuming sugar. However, there is ambiguity regarding the effects on human health that nonnutritive sweeteners can cause. The literature and research findings regarding this topic are diverse and controversial. This study aimed to explore the awareness, perceptions and knowledge of university students regarding NNSs. An online and in-person survey was distributed among students, and it was completed by 720 participants aged 18 to 65 years. The results showed a moderately positive perception of NNSs; this was explained by a significantly positive perception of their potential in reducing the risk of diabetes, as indicated by 30% of respondents. However, 38% of respondents perceived the use of NNSs and their potential undesirable health effects as more risky than beneficial. Additionally, a strong trust in government agencies and health professionals was identified, with 30% of respondents agreeing and 29% of respondents strongly agreeing that they trusted them. Hence, partial consistency was observed, with similar research highlighting the need for more initiatives to raise awareness regarding health topics, such as NNSs, specifically concerning health risk perceptions and awareness. The results provide an opportunity for further investigation to identify the public’s understanding and perceptions of NNSs, which will contribute to the development of more effective targeted public health campaigns.