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Synthesis and Structural Characterization of 1,4-Diazepines Related to Curcumin
Published:
30 October 2015
by MDPI
in The 19th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
The reactivity of (E)-5-(4-hydroxy-3-methoxyphenyl)-1-phenylpent-4-ene-1,3-dione with ethylenediamine has been studied in different experimental conditions. Two dihydro-1,4-diazepines have been obtained and fully characterized by 1D and 2D multinuclear NMR spectroscopy and HRMS.
Keywords: 1,4-diazepines, curcumin, 1H, 13C, 15N NMR
Comments on this paper
Sunil Gaikwad
2 November 2015
Organic chemistry
why you have not taken single crystal of both Compounds 3 and Compound 4.
This is very interesting work simple and easy workout in the simple laboratory.
Have you chick their biological activity?
good work.
This is very interesting work simple and easy workout in the simple laboratory.
Have you chick their biological activity?
good work.
Dionisia Sanz
3 November 2015
Unfortunately for the moment we have no crystals suitable for X-ray structure.
Yet we have not made any biological tests, but we intend to do them
Yet we have not made any biological tests, but we intend to do them