Please login first
Pentafluorophenylammonium triflate (PFPAT): an efficient, practical, and cost-effective organocatalyst for bigginelli reaction
, *
1  Chemistry Department, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran

Abstract: A simple, inexpensive, environmentally friendly and efficient route for the synthesis of 3,4-dihydropyrimidin-2(1H)-one derivatives via the one-pot three-component Biginelli reaction using pentafluorophenylammonium triflate (PFPAT) as a catalyst is described. PFPAT organocatalyst is air-stable, cost-effective, easy to handle, and easily removed from the reaction mixtures.
Keywords: Pentafluorophenylammonium triflate● Organocatalyst ● Acidity● 3,4-dihydropyrimidin-2(1H)-one● Biginelli
Top