A copper-based metal-organic framework with 1, 3, 5-tricarboxylic acid linkers was prepared through a facile hydrothermal method. This MOF has not been used in organic reactions widely. Cu.BTC was employed as an affordable, competent heterogeneous catalyst in 1, 8-dioxo-octa-hydro xanthene synthesis. Additionally, the structure, morphology, and porosity of this catalyst were considered. Various techniques such as FE-SEM, BET, EDS, FT-IR, and XRD applied to this aim. As a result, Cu.BTC had a mesoporous structure, an excellent specific surface area, and high purity. Some privileges of using this heterogeneous catalyst in 1, 8-dioxo-octa-hydro xanthene synthesis are mild condition, increased activity, ease in separation, and reusability. Also, 1, 8-dioxo-octa-hydro xanthene was obtained via simple recrystallization.