EventsThe 16th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-16-01062
This submission belongs to the session a. General Organic Synthesis of the event The 16th International Electronic Conference on Synthetic Organic Chemistry
Published date
26 Oct, 2012
Citation
Amira M Mohamed, Azza M El-Kazak, Tarik E Ali, Magdy A Ibrahim, Synthesis and Chemical Reactivity of the Novel 6,8-Dibromo-7-hydroxychromone-3-carboxaldehyde, in Proceedings of The 16th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2012, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-16-01062
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Synthesis and Chemical Reactivity of the Novel 6,8-Dibromo-7-hydroxychromone-3-carboxaldehyde

Magdy A Ibrahim 1
Tarik E Ali 1
Azza M El-Kazak 1
Amira M Mohamed 1
1. Department of Chemsity, Faculty of Education, Ain Shams University
Abstract
A novel 6,8-dibromo-7-hydroxychromone-3-carboxaldehyde (4) was prepared from the Vilsemier-Haack formylation of 3,5-dibromo-2,4-dihydroxyacetophenone. The chemical reactivity of carboxaldehyde 4 was studied towards some hydrazine derivatives under different reaction conditions. 1,3,4-Thiadiazol-2-ylchromone derivative 10 was also prepared. The chemical behavior of carboxaldehyde 4 was studied towards hydroxylmine hydrochloride under different reaction conditions to produce compounds 11-14. The reaction mechanism and mass spectrometry for some compounds were also reported.
Keywords
chromone-3-carboxaldehyde
nucleophilic reactions
ring opening ring closure reactions
mass spectrometry.
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