Title: Roasted whole grain Barnyard millet flour effective in reversing metabolic sign of diet-induced metabolic syndrome rats

Millet is recognized as one of the beneficial cereals that can provide adequate nutrients and several studies have demonstrated that supplementation of millet has potential to possess valuable effects on the lifestyle disorder. However, the possible benefits of barnyard millet to the metabolic disorder disease are very limited . New insight in this area is important to improve the variety of healthy diet to the consumer especially to individual with metabolic syndrome. Thus, this study aimed to determine the effect of roasted whole grain barnyard millet flour on the diet-induced metabolic syndrome rats. We investigated the reversal sign of the metabolic syndrome of male Wistar rats on 10% addition of roasted whole grain barnyard millet flour to modified high carbohydrate high fats diet and corn starch diet for the final eight weeks of a 16-week protocol. The rats were divided into 5 group (n=8) and each of the group received special diet for 16 weeks: normal rats’ pallet (N), corn starch diet with barnyard millet (CM), corn starch diet (CS), high-carbohydrate high-fats diet with barnyard millet (HM) and high-carbohydrate high-fats diet (HF). After 16 weeks of diet regime, the intervention rats’ group CM and HM has a significant reduction (P<0.05) in fat mass, blood glucose tolerance between week 8 and week 16, and shows a significant difference (P<0.05) in weight, abdominal circumference, blood pressure between group CM with CS and group HM with HF. The results demonstrated the important potential of roasted whole grain barnyard millet health-promoting effect, specifically in reversing metabolic syndrome disease.