Events The 16th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 16th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Oct, 2012

Citation

Andrei I. Khlebnikov, Galina A. Domina, Andrei S. Potapov, Facile Synthesis of Bis(azolyl) Derivatives in a Superbasic Medium, in Proceedings of The 16th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2012, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-16-01107

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Facile Synthesis of Bis(azolyl) Derivatives in a Superbasic Medium

Andrei S. Potapov ¹

Galina A. Domina ¹

Andrei I. Khlebnikov ¹

1. Altai State Technical Universty

Abstract

Reaction of azoles (1,2,4-triazole, benzimidazole, bezotriazole) and dihalogenoderivatives of alkanes and oligoethyleneglykols in a superbasic KOH-dimethylsulfoxide medium was used for the synthesis of bis(azolyl)alkanes and related compounds. The new method does not involve the use of toxic solvents and catalysts, does not require column chromatography for product separation and gives the target compounds in high yields.

Keywords

1,2,4-triazole

benzimidazole

bezotriazole

alkylation

superbacis medium

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