Events The 16th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session b. Bioorganic, Medicinal and Natural Products of the event The 16th International Electronic Conference on Synthetic Organic Chemistry

Published date

26 Oct, 2012

Citation

ali Maleki, Mohammad Gorban Dekamin, Mohammad Eslami, Aqueous Synthesis of 2-Amino-tetrahydrobenzo[b]pyrans by a Green, Efficient and Simple Organocatalyst, in Proceedings of The 16th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2012, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-16-01115

Facebook

Twitter

Aqueous Synthesis of 2-Amino-tetrahydrobenzo[b]pyrans by a Green, Efficient and Simple Organocatalyst

Mohammad Eslami ¹

Mohammad Gorban Dekamin ¹

ali Maleki ¹

1. 1

Abstract

An efficient and convenient method has been developed for the synthesis of 2-amino-4H-tetrahydrobenzo[b]pyrans derivatives via one-pot , three-component condensation of malononitrile or ethyl cyanoacetete, dimedone and different aldehydes in the presence of a catalytic amount of potassium phthalimide-N-oxyl (POPINO), as a new organocatalyst, in aqueose media. A variety of 2-amino-tetrahydro[b]pyrans derivatives were obtained in high to excellent yield within short reaction times.

Keywords

Multicomponent reaction

dimedone

on water synthesis

2-amino-4H-tetrahydrobenzo[b]pyrans

potassium phthalimide-N-oxyl.

Synthesis, Molecular Docking Studies and Anti-mycobacterial Evaluation of N-(Malon-substituted-anilic)-4-phenyl Thiosemicarbazide

Studies of DNA Interactions with Functionalizedbenzo[a]phenoxazinium Chlorides