EventsThe 25th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-25-11674 (registering DOI)
This submission belongs to the session S2. Bioorganic, Medicinal and Natural Products Chemistry of the event The 25th International Electronic Conference on Synthetic Organic Chemistry
Published date
13 Nov, 2021
Academic Editor
author-avatarJulio A. Seijas
Citation
Didier Villemin, Mebrouka Dekhici, Nathalie Bar, Nawel Cheikh, Aerobic and biomimetic activation of C-H bonds of phenols catalyzed by copper-amine complexes, in Proceedings of The 25th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2021, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-25-11674
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Aerobic and biomimetic activation of C-H bonds of phenols catalyzed by copper-amine complexes

Mebrouka Dekhici 1
Didier Villemin 2
Nathalie Bar 3
Nawel Cheikh 1,4
1. Université de Bechar, Faculté des Sciences et Technologies, BP 417, 08000 Bechar, Algeria
2. Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, INC3M, FR 3038, ENSICAEN et Université de Caen Normandie, 14050 Caen, France, France
3. Laboratoire de Chimie Moléculaire et Thioorganique, UMR CNRS 6507, INC3M, FR 3038, ENSICAEN et Université de Caen Normandie, 14050 Caen, France
4. Laboratoire de Catalyse Et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, 13000, Tlemcen, Algeria
Abstract

Various copper complexes were prepared (CuCl(phen), Cucl(bipy), CuCl(neocu), CuCl(BPA), [CuCl(OH)(tmeda)]2 ) and tested in aerobic room temperature oxidation of p-cresol. The complexe [CuCl(OH)(tmeda)]2 was found has the more efficient and was used in o,o and p,p coupling of various phenols and in the formation of quinones under aerobic conditions. The dimerisation of substitued naphthols was also studied.

These C-H activation with formation of one C-C bond and one harmless molecule of water with air as oxidant at room temperature represent a biomimetic model of enzyme Laccase.

Keywords
green chemistry
aerobic oxidation
C-H activation
Cu complexe
phenols
Manuscript
sciforum_053817.pdf
Oral Presentation
sciOxCu.pptx
Poster
sciOxCu.pdf
sciOxCu.pdf
Study of Diels-Alder Reactions of Purpurogallin Tetra-Acetate with Various Dienophiles
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