Reaction of some substituted (un)substituted isatins with 1,ω-alkanes and their products with sodium azide

Azide derivatives of isatins were the needed initial materials for click chemistry in order to form 1,2,3-triazoles in order to synthesize the hybrid compounds of 1,2,3-triazole−isatin having monosaccharide moieties. Required substituted isatin were prepared according to Sandmeyer method from corresponding subsituted anilines. N-(ω-Bromoalkyl)isatins were prepared by nucleophilic reaction S_N2 of (un)substituted isatins with appropriate dibromoalkanes. Some ω-azidoalkylisatins were synthesized by reaction of corresponding ω-bromoalkylisatins with sodium azide. The reactions were performed in dry DMF as solvent in the presence of K₂CO₃ as base and KI as promotive agent. Product yields achived 30−85%.