EventsThe 25th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-25-11737 (registering DOI)
This submission belongs to the session S1. General Organic Synthesis of the event The 25th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2021
Academic Editor
author-avatarGyörgy Keglevich
Citation
Ramzi MAADADI, Chafai BOUKENTOUCHA, Maamar HAFFAS, Liza SAHER, Khaldoun BACHARI, Zahia KABOUCHE, In Situ Hemi-synthesis of new unexpected chiral chromeno-pyrimidine derivative, in Proceedings of The 25th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2021, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-25-11737
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In Situ Hemi-synthesis of new unexpected chiral chromeno-pyrimidine derivative

Ramzi MAADADI 1,2
Chafai BOUKENTOUCHA 3
Maamar HAFFAS 1,4,5
Liza SAHER 1
Khaldoun BACHARI 1
Zahia KABOUCHE 2
1. Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques (CRAPC), 42000 Tipaza, Algeria
2. Université des frères Mentouri-Constantine 1, Département de chimie, Laboratoire d’Obtention des Substances Thérapeutiques (L.O.S.T), Campus Chaabet-Ersas, 25000, Constantine, Algeria
3. Université des Frères Mentouri Constantine 1, Unité de Recherche de Chimie de l’Environnement et Moléculaire Structurale CHEMS, 25000 Constantine, Algeria
4. Laboratoire de Recherche Biotechnologie des Molécules Bioactives et de la Physiopathologie Cellulaire ; faculté des sciences de la nature et de la vie de l’université de BATNA 2
5. Université des frères Mentouri-Constantine, Département de chimie, Laboratoire d'Obtention des Substances Thérapeutiques (L.O.S.T), Campus Chaabet-Ersas, 25000 Constantine, Algeria
Abstract

A hemi-synthesis reaction of barbituric Acid with an α,β-unsaturated aldehyde using Perillaldehyde from Essential oil of Ammodaucus leucotrichus subsp leucotrichus, affording to a chromeno-pyrimidine derivative. The reaction was carried out in Water/Ethanol medium without an added catalyst. The obtained pyrimidine was identified by their spectral 1H, 13C, HMBC and HSQC 2D NMR.

Keywords
Hemi-synthesis
Barbituric Acid
Chromeno-Pyrimidine
Chiral Perillaldehyde
Manuscript
sciforum_051602_original_Mans_MAADADI-done.pdf
Oral Presentation
MAADADI ECSOC25.pptx
Poster
MAADADI ECSOC25.pdf
MAADADI ECSOC25.pdf
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