EventsThe 25th International Electronic Conference on Synthetic Organic Chemistry
Event submissions
Published
with-doi10.3390/ecsoc-25-11796 (registering DOI)
This submission belongs to the session S2. Bioorganic, Medicinal and Natural Products Chemistry of the event The 25th International Electronic Conference on Synthetic Organic Chemistry
Published date
14 Nov, 2021
Academic Editor
author-avatarJulio A. Seijas
Citation
Mohammad G. Dekamin, Hamidreza FaniMoghadam, Negin Rostami, Novel magnetic 4-aminobenzenesulfonic acid-functionalized periodic mesoporous organosilica as a highly efficient and reusable nanocatalyst for the sustainable synthesis of dibenzo[1,4]diazepine derivatives, in Proceedings of The 25th International Electronic Conference on Synthetic Organic Chemistry, 15 November–30 November 2021, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-25-11796
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Novel magnetic 4-aminobenzenesulfonic acid-functionalized periodic mesoporous organosilica as a highly efficient and reusable nanocatalyst for the sustainable synthesis of dibenzo[1,4]diazepine derivatives

image
Hamidreza FaniMoghadam 1
Mohammad G. Dekamin 2
Negin Rostami 1
1. Pharmaceutical and Heterocyclic Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran
2. Pharmaceutical and Heterocyclic Compounds Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran, 16846-13114, Iran, Hong Kong
Abstract

New magnetic 4-aminobenzenesulfonic acid (PABSA)-functionalized periodic mesoporous organosilica (Fe3O4@PMO-ICS-Pr-PABSA) was prepared as a green and recoverable nanocatalyst. This nanocatalyst was able to efficiently catalyze synthesis of dibenzo[1,4]diazepine derivatives via one-pot three-component reactions of o-phenylenediamine, dimedone and various aldehydes at room temperature. This method have the key advantages such as simplicity of operation, high to excellent products yield and short reaction times, easy work-up, accessible catalyst and purification of products by crystallization (non-chromatographic) of this work.

Keywords
Magnetic 4-aminobenzenesulfonic acid-functionalized periodic mesoporous organosilica
dibenzo[1,4]diazepine derivatives
Three-Component reactions
Nanocatalyst.
Manuscript
sciforum_052845.pdf
Poster
Green synthesis of dibenzo-1,4-diazepine .pdf
Green synthesis of dibenzo-1,4-diazepine .pdf
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