Events The 12th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 12th International Electronic Conference on Synthetic Organic Chemistry

Published date

14 Nov, 2008

Citation

M. José Alves, Américo Lemos, José Enrique Rodriguez-Borges, Xerardo García-Mera, Ethyl 2-(Diisopropoxyphosphoryl)-2H-Azirine-3-Carboxylate: Reactions with Activated 1,3-Butadienes, in Proceedings of The 12th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2008, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-12-01222

Facebook

Twitter

Ethyl 2-(Diisopropoxyphosphoryl)-2H-Azirine-3-Carboxylate: Reactions with Activated 1,3-Butadienes

M. José Alves ¹

Américo Lemos ²

José Enrique Rodriguez-Borges ³

Xerardo García-Mera ⁴

1. Departamento de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal

2. Departamento de Química, Bioquímica e Farmácia, Universidade do Algarve, Campus de Gambelas, 8005-137 Faro, Portugal

3. CIQ, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, 4169-007 Porto, Portugal

4. Departamento de Química Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, E-15782 Santiago de Compostela, Spain

Abstract

Ethyl 2-(diisopropoxyphosphoryl)-2H-azirine-3-carboxylate was generated “in situ” and reacted with a number of 1,3-butadienes. Cycloadducts, or in one case an ensuing rearranged product, were isolated with moderate to good yields.

Keywords

2H-Azirines

aza-Diels-Alder cycloaddition

dienophiles

phosphonate derivative compounds

Halogenated Thiophenes as Precursors in the Preparation of Halogenated and Arylated Anthraquinones

Solvent-free synthesis of Pyridine-2-aminium-6-methyl Pyridine-2,6-dicarboxylate under ball-milling conditions