Events The 11th International Electronic Conference on Synthetic Organic Chemistry

Event submissions

Published

This submission belongs to the session a. General Organic Synthesis of the event The 11th International Electronic Conference on Synthetic Organic Chemistry

Published date

30 Nov, 2007

Citation

S. M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Convenient Synthesis of Novel Amino Acid Coupled Benzanilides, in Proceedings of The 11th International Electronic Conference on Synthetic Organic Chemistry, 1 November–30 November 2007, MDPI: Basel, Switzerland, doi: 10.3390/ecsoc-11-01299

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Convenient Synthesis of Novel Amino Acid Coupled Benzanilides

S. M. El Rayes ¹

Ibrahim A. I. Ali ¹

Walid Fathalla ²

1. Department of Chemistry, Faculty of Science, Suez Canal University, Ismailia, Egypt

2. Department of Mathematical and Physical Sciences, Faculty of Engineering, Suez Canal University, Port Said, Egypt

Abstract

A facile and convenient synthesis of a variety of Methyl 2-(2-Benzoylaminobenzoylamino) alkanoate 4a-d has been developed by the DCC coupling of 2- Benzoylamino-benzoic acid with amino acid methyl ester. Compounds 4a-c were alternatively prepared by the reaction of aminoacid ester with 3,1-benzoxazinone 2 in pyridine. Dipeptides 8a-j were subsequently prepared following the azide coupling method. Compounds 4 and 8 were expected to possess antimicrobial activity.

Keywords

antibiotics

TCS

amino acids and dipeptide

DCC and azide coupling

benzanilides

3,1-benzoxazinone

Synthesis of New 1-Substituted-4-(2-phenylquinazolin-4-yl and 4-ylidene)

Quantitative Regeneration of Carbonyl Compounds from Oximes and hydrazones by Gaseous Nitrogen Dioxide